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COVID19 vaccine

COVID19 vaccine clinical trials – over 30 candidates being tested on humans

This article about COVID19 vaccine trials will be regularly updated as new clinical trials are registered or early results are published about an ongoing trial. Again, this article will focus on COVID19 vaccine trials – treatments and diagnostic tests are outside of the scope of this article.

Keeping up with COVID19 vaccine candidates has gotten out of hand, so for brevity, I’ve created a separate list of coronavirus vaccine trials. The interest in clinical trials for a new COVID19 vaccine is unprecedented, so I thought this might be the best way to keep loyal readers up-to-date.

Recently, the World Health Organization (WHO) has listed over 140 COVID19 vaccine candidates, which is amazing, but it is way too difficult to tell which ones have any chance of actually becoming a real product.

Right now, there are at least 30 COVID19 vaccine candidates in clinical trials – this article will analyze these coronavirus vaccine trials. Every single day, a new COVID19 vaccine candidate enters clinical trials, so this may be out of date within a few hours! 

Read More »COVID19 vaccine clinical trials – over 30 candidates being tested on humans

Russian coronavirus vaccine

Russian coronavirus vaccine – tested by showing it a photo of the word “test”

A new Soviet Russian coronavirus vaccine, called “Sputnik V” was approved by the Soviet Union Russia. The “first” vaccine to be approved was announced by Soviet General Secretary Russian President Vladimir Putin, otherwise known as Donald Trump’s best friend forever.

Amusingly, the “Sputnik V” name harkens back to the Space Race, a Cold War competition between the USA and the Soviet Union in the 50s and 60s to see which country could build the best space program. Sputnik was the name of the first orbital satellite launched by the Soviets beating the USA to space by two months. It didn’t really do much but beep every few seconds while orbiting the earth – we’ll take that as an excellent metaphor.

Not to be totally cynical, the name is an obvious propaganda statement by Putin that the Soviets Russians won the coronavirus vaccine war. 

Of course, the scientist in me says “not so fast there Comrade.” Let’s take a look at the science, or better still the lack of science, of this new Russian coronavirus vaccine. Considering how skeptical I am of the US coronavirus vaccine effort, you can imagine what I’m going to write about Putin’s effort. Read More »Russian coronavirus vaccine – tested by showing it a photo of the word “test”

Lyme disease vaccine

Lyme disease vaccine update – very good news from clinical trials

Time to talk about something different (you know, all coronavirus, all the time) like a potential Lyme disease vaccine. A new vaccine for this terrible disease has just completed phase 2 clinical trials, and the results look promising.

As opposed to the mad rush to get a COVID-19 vaccine, this new Lyme disease vaccine has taken several years just to get to this point. But the news is good, so there’s that.

Of course, dogs have had access to a Lyme disease vaccine, but there has not been a vaccine available for humans for 18 years. It’s not that dogs are more important than humans (though many of us might argue that point), it’s just that about 20 years the anti-vaxxers, one of their few “successes,” got the vaccine pulled from the market

But a small company, Valneva, is getting a good vaccine moving down the development pathway. Hopefully, we’ll have it in a few years.

Let’s take a look at this disease.

Read More »Lyme disease vaccine update – very good news from clinical trials

hydroxychloroquine

Hydroxychloroquine ineffective for COVID-19, demon sperm, and zombies

Just when I thought I was out of the hydroxychloroquine pseudoscience, they pull me back in. And here we are, a group of fools is pushing it again. Sigh.

This all started because of an awful study from France published back in March of 2020. At that time, Donald Trump, desperate for a “win” against the coronavirus along with other non-scientists pushed hydroxychloroquine and azithromycin for coronavirus. Of course, me and many others like Orac, who has written several articles about it,  found the evidence that hydroxychloroquine, usually with the antibiotic azithromycin, had any effect on COVID-19 was very weak, even non-existent. 

And my mind hasn’t been changed in the meantime. And Orac is back calling hydroxychloroquine the “Black Knight,” a reference to a fictional character in the wonderful film, Monty Python and the Holy Grail. Oh, you never saw the movie? Well, I’ll let Orac tell that story:

In the film, King Arthur encounters him guarding a rather pathetic bridge and asks him to join his quest to seek the Holy Grail. The Black Knight refuses and then blocks Arthur’s passage with a menacing, “None shall pass.” The battle is joined, and Arthur, one by one, chops off all of the Black Knight’s limbs in a truly warped comedy sequence. After losing each limb, the Black Knight says things like, “‘Tis but a scratch” and “I’ve had worse.” Before his last leg is chopped off, the Black Knight proclaims (while hopping around), “I’m invincible,” to which Arthur retorts, “You’re a loony.” After losing his last limb, the Black Knight finally concedes, “All right, we’ll call it a draw.” Then, as Arthur crosses the bridge and rides off, the Black Knight yells, “Oh. Oh, I see. Running away, eh? You yellow bastards! Come back here and take what’s coming to ya! I’ll bite your legs off!”

In other words, this damn story about hydroxychloroquine keeps coming back despite having all of its limbs removed. “Tis but a scratch.” 

Now, I prefer zombie metaphors (and I believe so does Orac, but I have to give credit to him for the Monty Python reference), because, like many of the tropes we see in the anti-vaccine world, no matter how many times we kill this belief, it keeps coming back. In the world of zombies, one needs to destroy the brain. That’s why I try to present evidence!

Of course this time around, this claim includes demon sperms and alien DNA. I kid you not.

Read More »Hydroxychloroquine ineffective for COVID-19, demon sperm, and zombies

Robert F Kennedy Jr

Robert F Kennedy Jr used Alan Dershowitz in anti-vaccine fake debate

This article, about an anti-vaccine fake debate between Robert F Kennedy Jr and Alan Dershowitz was used to promote anti-vaccine misinformation, was written by Dorit Rubinstein Reiss, Professor of Law at the University of California Hastings College of the Law (San Francisco, CA), who is a frequent contributor to this and many other blogs, providing in-depth, and intellectually stimulating, articles about vaccines, medical issues, social policy, and the law.

Professor Reiss writes extensively in law journals about the social and legal policies of vaccination. Additionally, Reiss is also a member of the Parent Advisory Board of Voices for Vaccines, a parent-led organization that supports and advocates for on-time vaccination and the reduction of vaccine-preventable disease.

On July 23, 2020, anti-vaccine activists aired what they described as a heated debate between Attorney and Professor Alan Dershowitz and anti-vaccine activist Robert F Kennedy Jr. The “debate” was a good example of why debating anti-vaccine activists is a bad idea.

Basically, Kennedy did most of the talking, and most of his talk was not – as initially suggested – about the law, but a recitation of anti-vaccine talking points, most of them either misleading or blatantly untrue. Dershowitz, who is not a public health expert or a debunker of anti-vaccine misinformation, was not prepared to address them. While he did push Kennedy on some issues, with Kennedy’s misinformation left unaddressed, viewers may come out with the impression that Kennedy’s points had merit.

The points do not. Robert F Kennedy Jr consistently misrepresented the facts, and was not quite accurate on the constitutional law, though he was closer. He misrepresented the regulatory framework on vaccines. In essence, Kennedy used this as an opportunity to share misinformation while using Dershowitz’s comparable legitimacy to give weight to his claims.Read More »Robert F Kennedy Jr used Alan Dershowitz in anti-vaccine fake debate

moderna vaccine

Moderna vaccine update – are we too excited about it for COVID-19

If you have been paying attention to the news, you’ve probably seen reports of the Moderna coronavirus vaccine candidate that is getting a lot of people very excited. I’ve even seen so-called pro-vaccine people, who ostensibly should be following science, breathlessly cheer them on.

Recently, Moderna had released some results in a press release, and you know what I think about press releases. Unfortunately, many vaccine researchers stated that that data was not sufficient to draw any conclusions about the safety or effectiveness of the Moderna vaccine.

However, the phase 1 clinical trial results have been published, and the hype has started again. We’ll take a brief look at those results below.

I know that people want “hope,” as opposed to possibly endless cycles of bouncing between opening up and closing down everything in response to the pandemic, especially in the USA, where the coronavirus pandemic has just gotten worse.

But hope isn’t something that interests me at all.

As anyone who reads my blog knows that the only thing that matters to me is published scientific evidence. And by published, I mean in a respected, peer-reviewed journal. Sure, I don’t need scientific evidence to support my belief that the New York Mets should be thrown out of baseball, because I hate the team – that’s just an opinion. It’s not based on evidence of any type.

On the other hand, when it comes to vaccines, we have built an amazing system of bringing the most effective and safest medical advances to humanity. Despite the misinformation and FUD of the anti-vaccine zealots, the safety and effectiveness of modern vaccines are settled science.

I’m not willing to sacrifice that for a vaccine that may not be effective or safe. That’s why I want to take a very critical look at the Moderna vaccine. And I think there are some reasons to be very concerned about their vaccine, although there might be some reasons to be somewhat optimistic.Read More »Moderna vaccine update – are we too excited about it for COVID-19

bcg vaccine for coronavirus

BCG vaccine for coronavirus – Can it work? Or is this a shot in the dark?

I originally wrote this article about the BCG vaccine for coronavirus about three months ago (that’s about 10 years in non-pandemic time measurement). Of course, as things happen with the coronavirus pandemic, ideas keep returning, and I wanted to make sure that this article is up-to-date with the most recent information about whether the BCG vaccine has any usefulness in preventing or improving outcomes of COVID-19.

I wanted to see if there was any evidence supporting the BCG vaccine for coronavirus, so here’s what I found.Read More »BCG vaccine for coronavirus – Can it work? Or is this a shot in the dark?

coronavirus vaccine trials

Coronavirus vaccine trials – updating current studies across the world

This article about coronavirus vaccine trials will has been substantially updated and published here. Please go there for the most up-to-date information about these vaccines.

Keeping up with COVID-19 vaccine candidates has gotten out of hand, so for brevity, I’ve created a separate list of coronavirus vaccine trials. The interest in clinical trials for a new COVID-19  vaccine is unprecedented, so I thought this might be the best way to keep loyal readers up-to-date.

Recently, the World Health Organization (WHO) has listed over 140 vaccine candidates, which is amazing, but it is way too difficult to tell which ones have any chance of actually becoming a real product.

Right now, there are 16 vaccine candidates in clinical trials – this article will analyze these coronavirus vaccine trials. Of course, this number changes from week-to-week, so who knows what it will be the next time I update this article!

Read More »Coronavirus vaccine trials – updating current studies across the world

coronavirus vaccine skeptic

Coronavirus vaccine skeptic – why I am uneasy about a new vaccine

The more I read about the rush for a new vaccine, the more I am becoming a coronavirus vaccine skeptic. I think that we’re doing this all wrong, and I think that this vaccine could be a disaster if it is rushed to the market.

Because too many people don’t read articles beyond the title, like anti-vaxxers who can’t be bothered to delve into the science beyond abstracts, I want to be clear about something. All vaccines available today are overwhelmingly safe and effective – any possible issues with vaccines are substantially smaller than the harm caused by the disease.

This is settled science.

I am a passionate supporter of all vaccines, anyone who reads this blog knows that. I am only a coronavirus vaccine skeptic – and just to be clear again, I am a scientific skeptic which means I follow evidence derived from the scientific method to a conclusion. 

My coronavirus vaccine skepticism, at least right now, is based on the fact that there is little evidence supporting either it’s effectiveness or safety, although those are not really issues because we are very early in the development of these vaccines. My skepticism is in the methods that we are employing to rush this vaccine to market.

This is totally different than your typical anti-vaccine zealots like Del Bigtree  Littletree and RFK Jr who ignore all scientific evidence to push their anti-vaccine narrative. 

Although I’ve written about my concerns regarding our rush to get a vaccine previously, I’ve made more observations that bother me.Read More »Coronavirus vaccine skeptic – why I am uneasy about a new vaccine

coronavirus pandemic

The coronavirus pandemic – just as bad for Trump supporting states

This article about how the coronavirus pandemic will affect conservative red states was written by a database expert who wishes to remain anonymous.

Among my more right-leaning Facebook friends, the attitude towards the coronavirus pandemic goes roughly like this: “The outbreak isn’t anywhere near as bad as the Liberal Media would have you believe. It’s almost entirely confined to sanctuary cities. Everyone should stop overreacting!”

For everyone else, this attitude seems delusional. But for people who live in right-wing communities, the “it’s not so bad” point of view is actually in line with observed reality. And the way that the media has been reporting on the outbreak actually exaggerates this effect.Read More »The coronavirus pandemic – just as bad for Trump supporting states