Here we go again – bad published research tries to convince us that COVID-19 rates are unrelated to the uptake of COVID-19 vaccines in several countries and US counties. That would be interesting if not for the poor design and analytical methodology utilized by these researchers.
Of course, the second this kind of paper is published, every COVID-19 denier jumps on board to say “here’s the official proof that the COVID-19 vaccines are useless.”
I’m going to set aside the irony that anti-vaxxers love to argue that the bulk of vaccine research is garbage, usually bought by Big Pharma. But any “research” that supports their pre-conceived conclusion is, of course, Nobel Prize-worthy.
It’s frustrating, but my job is to critique this type of research. And this new paper that states that COVID-19 rates are not related to uptake levels of vaccines is a prime example of research filled with bad methodology, poor analytical procedures, and lots of bias.
In case you don’t know of her, Professor Smith is a solid pro-vaccine researcher with an impressive list of published articles. It’s ironic that Smith publishes real science about the zombie apocalypse in respected journals, whereas anti-vaxxers can’t publish their “research” in anything but predatory journals.
But let’s stick with the zombie apocalypse, because if there’s anything that makes it feel like we’re in a dystopian future with zombies, it’s the current COVID-19 pandemic.
This article about how the coronavirus pandemic will affect conservative red states was written by a database expert who wishes to remain anonymous.
Among my more right-leaning Facebook friends, the attitude towards the coronavirus pandemic goes roughly like this: “The outbreak isn’t anywhere near as bad as the Liberal Media would have you believe. It’s almost entirely confined to sanctuary cities. Everyone should stop overreacting!”
I am fairly certain that most of the feathered dinosaur’s readers have read articles about alcohol health effects. It’s bad. It’s good. It prevents heart attacks. It causes cancer. It reduces risks of Sasquatch attacks but increases risks of alien abductions.
I know some of you are thinking that science never gets this right. Who are you to believe? An ancient feathered dinosaur? Your favorite news website? Your next door neighbor? Alien Sasquatch?
Firearms mortality, either murder, accidental or suicide, has always been a public health issue in the USA. There have been several good epidemiological studies that have examined whether gun control regulations and firearms mortality risk are related – and the results are surprisingly vigorous.
From recent epidemiological research, there is some convincing evidence that establishes a correlation between state-level gun control regulations and firearms mortality rates. However, the link is not as black and white as one might wish – the relationship between firearms regulations and mortality depends on the quality of the law.
The nation’s leading public health organization, the Centers for Disease Control and Prevention (CDC), is essentially prevented from analyzing and publishing any epidemiological research that would help us understand what, if any, links there are between gun control and firearms mortality. The Republican dominated congress have done everything they can to prevent the CDC from using any funds to study the issue.
Furthermore, because the CDC cannot (or will not) fund research into gun control, it has lead to a chilling effect on gun control research in academia. According to the Washington Post, “young academics were warned that joining the field was a good way to kill their careers. And the odd gun study that got published went through linguistic gymnastics to hide any connection to firearms.”
It has been demonstrated that passively reported data, that is, data that isn’t actively investigated by trained researchers, cannot be used to assess causality. In an active investigation, it was found that only 2 of the 107 deaths had an autopsy performed, and most of the others had other underlying diseases and conditions that were causally related to the mortality events. Furthermore, 15 million people were vaccinated with the H1N1 seasonal vaccine, and it would be expected that there would be >8000 deaths during the 20 days after vaccination using a crude mortality rate in Japan. Though it would still be a misuse of statistics, there really is more evidence that the H1N1 vaccination lowered the background death rate from 8000 to 107 post vaccination. Continue reading “Properly evaluating vaccine mortality – let’s not abuse VAERS”
Zombie research has come to a scientific consensus that a true zombie must meet three criteria (for an exception, see Note 1):
It is a reanimated human corpse,
it is relentlessly aggressive, and
it is biologically infected and can pass that infection to healthy humans.
Recently, a researcher on the science of zombies, Tara C Smith (see Notes 2 and 3 ), an associate professor of biostatistics at Kent State University, published a review article on zombie epidemiology in BMJ, which examines the history, epidemiology, prevention, and treatment of zombie infections. I will endeavor to review some of the more important points as a service to my loyal readers.
The CDC recently published robust evidence that supports rotavirus vaccine effectiveness. There is nothing more powerful than epidemiological studies that show a correlation (and causality) between the drop in the incidence of a vaccine preventable disease immediately after wide introduction of a the vaccine itself in a relatively closed population.
One of the enduring zombie tropes of the junk science world is that cancer rates are increasing in the USA (and across the world), and that deaths from cancers are higher today than it was in the past. Depending on the one screaming this myth, this rate of cancer increase is a result of A) vaccines, B) GMO crops, C) pasteurized milk, D) non-organic foods, or E) everything.
To be certain, there are a few things that do cause cancer, like smoking, UV radiation, human papillomavirus, and obesity. There are no 100% guaranteed environmental risks that cause cancer (lots of smokers do not get lung cancer, and there are very rare cases of non smokers getting the same cancer).
But are cancer rates increasing?
Here and there, you might run across a study that mentions one thing or another may or may not increase or reduce the risk of cancer. But most of those studies are one-off primary research, usually using small groups, providing little clinical evidence that you may or may not be able to increase or decrease the risk of cancer. Wait until we can find these studies in large systematic reviews, before deciding that this or that may or may not increase or decrease the risk of cancer.
Updated 4 November 2014 to add some ironic analysis of Doshi’s “not-an-epidemiologist” background.
A few months ago, I wrote an article about Peter Doshi, a Ph.D. who is doing some postdoctoral work at Johns Hopkins University, one of the leading institutions of higher learning in the USA. Doshi is truly not very notable in science, except last year, he wrote an article about flu vaccines, basically employing the Nirvana Fallacy that because flu vaccines aren’t 100% effective they are worthless. Since vaccines are fundamentally a medical procedure to mitigate risk with a very low risk of adverse events, even 50% effectiveness will save thousands of lives. But we’ll get back to that.
The article he wrote is not actually based on real research, but appears to be an opinion paper–kind of like the opinion papers written by creationists who want to convince anyone who will listen that dinosaurs lived with humans. Doshi denies that most flu’s are even caused by the influenza virus. I guess the CDC’s high tech diagnostic tests for influenza are all wrong. But then again Doshi presents no evidence.