Although it may seem like all we talk about are the COVID-19 vaccines, but there’s more going on out there. One is a new breakthrough malaria vaccine that may bring an end to this scourge.
We are still a few years away from this vaccine being widely available, but since control of malaria has been a goal of scientists for a long time, a potential malaria vaccine is something that should be celebrated widely. Continue reading “Malaria vaccine clinical trials – a breakthrough in stopping a deadly disease”
One of the enduring myths about vaccines is that they’re rushed to market, which has continued with COVID-19 vaccines. This myth doesn’t arise because the anti-vaxxers have some “gotcha” information about these vaccines, it’s because they are intent on pushing fear, uncertainty, and doubt.
If you read my articles since March about the development of this vaccine, I was very troubled about the speed of development. Most vaccines take 5-10 years to develop, mostly because we want a better handle on the expected effectiveness and to uncover any potential (and extremely rare) serious adverse events.
But were the COVID-19 vaccine rushed? Not really. Basically, two massive resources – money and brainpower – were thrown at developing a vaccine so that we could stop the inexorable march of the pandemic. The best scientists in the world collaborated with the best pharmaceutical companies with the backing of the richest countries to develop and manufacture safe and effective vaccines.
It wasn’t a magical process where scientists pulled ideas out of thin air to make these vaccines using dangerous technologies. They didn’t.
We know how to train the adaptive immune system to prevent pathogenic diseases with vaccines using all kinds of technologies. Once we were able to isolate the SARS-CoV-2 virus and determine what parts of its structure were the most immunogenic, we knew what to do, it wasn’t a huge mystery at that time.
Continue reading “COVID-19 vaccines rushed? Another anti-vaccine myth without merit”
After the emergency use authorizations (EUA) were given for the Moderna and Pfizer COVID-19 vaccines, what is next in the pipeline? There are three vaccines that could be reviewed by the Vaccines and Related Biological Products Advisory Committee (VRBPAC) during the next few weeks that would provide recommendations to the FDA (and other national drug regulatory bodies) for EUAs.
The three vaccines I’m going to discuss are ones that have a reasonable chance of getting approved for use in the USA or Europe. This excludes COVID-19 vaccines from Russia, China, and other countries that rarely, if ever, get FDA approval for vaccines (see Note 1).
So, let’s take a look at what are probably the next three COVID-19 vaccines in the pipeline.
Continue reading “COVID-19 vaccines pipeline – potential next emergency use authorizations”