New vaccines wishlist — I am looking beyond COVID-19

new vaccines

I once was accused of not being opposed to any vaccine on the market, but little did they know I have a wishlist for new vaccines that goes beyond all that. Believe it or not, there are pathogens out there that still have a deleterious effect on the health of mothers, children, and everyone.

I just wanted to spend a bit of time talking about some of the diseases where new vaccines could improve health outcomes in significant ways. Let’s take a look at some of them.

Continue reading “New vaccines wishlist — I am looking beyond COVID-19”

Who is to blame for high insulin prices in the USA? Big Pharma?

insulin prices

Insulin prices are a big issue in the USA because they seem to be skyrocketing upwards much faster than inflation or anything else. Of course, people are blaming Big Pharma, because they seem to be the major culprits behind the gouging of diabetics.

However, like everything else, the facts behind insulin prices are much more complicated than what you might be reading in the most recent Facebook meme or post about the subject. Because a 4-line meme is so much easier than writing a complicated article about the world of insulin prices.

And I’m going to try to guide you through the travesty of how pharmaceuticals are priced and how it’s a total mess. And remember, this is only about America’s pharmaceutical pricing mess — hopefully, the rest of the world does this better.

Continue reading “Who is to blame for high insulin prices in the USA? Big Pharma?”

New Sanofi GSK COVID vaccine shows good effectiveness

sanofi gsk COVID vaccine

I thought that the Novavax COVID-19 vaccine would be the last one, but Sanofi and GSK will soon be seeking Emergency Use Authorization (EUA) for a new vaccine in the USA (and other countries). Although you might yawn at another COVID-19 vaccine, there are some good reasons to put this Sanofi-GSK version on your radar.

Since most of us have not thought much about other vaccines lately, this article will review this new vaccine, just so we are up to speed. And I guess I have to update my charts for COVID-19 vaccine myths and facts.

Continue reading “New Sanofi GSK COVID vaccine shows good effectiveness”

New hexavalent vaccine protects children against 6 diseases

hexavalent vaccine

On 26 December 2018, Sanofi and Merck jointly announced (pdf) FDA approval for a new hexavalent vaccine called Vaxelis. The new vaccine was developed to vaccinate children aged 6 weeks to 4 years old to protect them against diphtheria, tetanus, pertussis (whooping cough), polio, hepatitis B, and Haemophilus influenzae type B (also known as Hib). Sanofi and Merck stated that the companies are setting up production, and the vaccine should be available in the USA by 2020.

This new (for the USA) hexavalent vaccine is intended for intramuscular injection as a 3-dose series given at 2, 4, and 6 months of age. However, the initial dose may be given to infants as early as 6 weeks. The vaccine may be used to complete the hepatitis B immunization series. However, one additional dose of a pertussis-containing vaccine must be added to the 3-dose hexavalent vaccine schedule to complete the immunization against pertussis.

This vaccine will reduce the number of separate vaccinations from at least 4 down to 1. Reducing the number of times an infant needs to receive a shot is a benefit to the child, the parents, and the healthcare workers who perform the vaccinations.

Sanofi, Merck, and GSK have produced various formulations of this hexavalent vaccine outside of the USA since 2000. Merck and Sanofi submitted the application for this vaccine to the FDA in 2014 after completion of phase III clinical trials, which included over 1400 infants. The clinical trial showed that the new vaccine was equivalent, in terms of safety and effectiveness, to the older series of individual vaccines.

As discussed previously, spurious claims that hexavalent vaccines lack antigens and other nonsense have been debunked.

I am not sure why this vaccine took nearly two decades to reach the US market, but I’m sure someone in the anti-vaccine religion will invent some ridiculous conspiracy theory to say why. Nevertheless, this hexavalent vaccine is a very important addition to the list of vaccines available in the USA.

In spite of the FDA approval, the CDC’s Advisory Committee on Immunization Practices will need to review all of the data again before making a recommendation to change the US vaccination schedule. That will probably happen during the next couple of years.

This new hexavalent vaccine is a great benefit to preventing diseases that harm our children. I’m glad it’s coming to the USA.

Citations

Mike Adams of Natural News – nuclear stupidity about Gorski

Mike Adams of Natural News attacks David Gorski

This story is about Mike Adams of Natural News, considered the number one lunatic of the pseudoscience and anti-science pushing American Loons (a particularly vile form of worldwide loons).

Mike Adams, who styles himself as the Health Ranger (more like the anti-Health Ranger), runs the anti-science website, Natural News. Adams claims that Natural News is a science-based natural health advocacy organization, led by himself, a proclaimed “activist-turned-scientist.”

If you know nothing else about Natural News, Adams has claimed he’s a better scientist than Neil DeGrasse Tyson. Yes, let that sink in for a few minutes. Tyson thinks that evidence should be studied to form a conclusion, you know, the scientific method. Adams thinks that he can invent a few lame experiments to confirm his preconceived beliefs. That’s pseudoscience, in its purest form.

Mike Adams’ anti-science beliefs includes just about every important scientific fact of our modern world. He is an AIDS denier (meaning he doesn’t think that AIDS is caused by HIV). He is anti-vaccination. He is an 9/11 truther. He is an Obama birther. He thinks chemtrails exist. He has advocated violence against GMO supporters.

Mike Adams of Natural News encompasses the totality of science denialism in one wonderful package. If you wonder why he’s such a lunatic, it’s really just to sell his junk medicine to a naïve public. Essentially, he has used his “pseudoscience to sell his lies to the public.”

You might think there are no other lines he can cross. But you would then be underestimating his skills in lying and attacking those who support real science.

Continue reading “Mike Adams of Natural News – nuclear stupidity about Gorski”

Freedom to ignore French vaccination program – a court case

french vaccination program

Samia and Marc Larère, parents to a three year old and fifteen months old, have decided not to vaccinate them. A criminal charge was brought against them, by the government of France, for not giving their three year old the required vaccines against diphtheria, tetanus and polio according to the French vaccination program.

They were charged under two legal provisions–a provision in the Code of Public Health (le code de la santé publique, art. L.3116-4) that imposes a find of 3750 euros and up to six months in jail for those who do not receive, or allow those under their guardianship to receive, mandatory vaccinations, including parents (“Le refus de se soumettre ou de soumettre ceux sur lesquels on exerce l’autorité parentale ou dont on assure la tutelle aux obligations de vaccination prévues aux articles L. 3111-2, L. 3111-3 et L. 3112-1 ou la volonté d’en entraver l’exécution sont punis de six mois d’emprisonnement et de 3 750 Euros d’amende”).

And a provision in the criminal code that criminalizes neglect of parental duties “to the point of risking the health… of a minor child”, with a fine of 30,000 euros and up to two years in prisons as penalty (article 227-17: “Le fait, par le père ou la mère, de se soustraire, sans motif légitime, à ses obligations légales au point de compromettre la santé, la sécurité, la moralité ou l’éducation de son enfant mineur est puni de deux ans d’emprisonnement et de 30 000 euros d’amende”).

The reason the Larères initially gave for declining to vaccinate their child was that they could not give her only the required vaccines–the only available vaccines, they said, had the required vaccines in combination with others, like Hepatitis B and meningococcal, which are not legally required and they were not willing to give the combination vaccine to their child.  Upon further probing, however, the couple admitted they received a vaccine containing only the required vaccines from Sanofi Pasteur, but still refused to vaccinate claiming that the vaccine contained a “toxic product”.

It may have been this vaccine (pdf). It’s unclear which ingredients they were referring to. The product contains a number of ingredients that may be used to raise concern among those unfamiliar with their role in vaccines and the principle that the dose makes the poison. In fact, in the tiny amounts in vaccines (pdf), none of these ingredients is toxic (pdf). Continue reading “Freedom to ignore French vaccination program – a court case”

Another flu vaccine myth – Big Pharma profits

another flu vaccine myth

There is a more general article – about the myth of Big Pharma vaccine profits – which has recently been updated and republished. 

The 2015-16 flu season is upon us, and that means it’s flu vaccine time again. And flu vaccine myth time. There is another flu vaccine myth – Big Pharma profits – that needs to be debunked.

Despite the availability of several flu vaccines, many people think that the flu is a painless, harmless disease, a belief belied by evidence. Wrong.

To put flu in perspective, in the USA, depending on the severity of the flu season, from 3,000 (which happened 25 years ago, and hasn’t been that low since) to 49,000 people die every year. Worldwide, about 250,000 to 500,000 people die from the flu every year. A flu pandemic, like the one in 1918, killed 50-100 million humans, much more scary than Ebola.

Of course, a fairly large group of people, including some who are pro-science (read, pro-vaccine), will fall into the arms of their favorite flu vaccine myth, and then refuse to get the flu vaccine. Given the dangers of the flu, and given the loss in productivity, income, and lives, you’d think that the flu vaccine would be near the top of health care needs for the average person.

My fellow blogger, Tara Haelle, spent numerous hours putting together the Top Myths about the flu vaccine. She debunks these myths completely out of the water. But antivaccination myths are never static, there’s always a new variant. Continue reading “Another flu vaccine myth – Big Pharma profits”

The breadth and depth of vaccine research

I have frequently stated that the breadth and depth of vaccine research, which provides solid evidence on the safety and effectiveness of vaccines, overwhelms the misinformation, logical fallacies, and conspiracies pushed by the Society for Promotion of Vaccine Preventable Diseases (that is, the antivaccine cult).

In other words, there is so much evidence, published in generally respected, high quality journals, that it is the basis of a pure, 24-karat gold scientific consensus about vaccine safety and effectiveness. Using just one search parameter, vaccines + efficacy + safety, there are over 4200 articles published over the past 55 years on vaccines. Other search parameters show even more results.

As I’ve said time and again, the only thing that matters to science is the quality and quantity of repeated evidence derived from a broad range of different studies. We’ve got that. Continue reading “The breadth and depth of vaccine research”

Improved high dose flu vaccine for seniors

flu-vaccine-seniorIt’s that time of year again, early autumn, when flu experts recommend getting the seasonal flu vaccine, especially for children and individuals over 65. Of course, if you don’t think you should get the vaccine, there’s a description for a person like you.

One of the issues that has been observed in the past is that the traditional flu vaccines may not have a high effectiveness in older adults. In fact, recent research shows that, in patients over 65 years old, the effectiveness of the flu vaccines can be as low as 9% for some strains of the influenza A virus (but still strong effectiveness for that group for other strains of influenza A and all strains of the influenza B virus).

The lower effectiveness may not be a result of the vaccine itself, but because older individuals may require more antigen to induce a proper immune response. Because of these observations, Sanofi Pasteur developed a high dose version of their Fluzone vaccine specifically for seniors. The new high dose vaccine contains 60 μg of each of the three hemagglutinin antigens per vaccine dose compared to the 15 μg per antigen in the standard Fluzone dose. Continue reading “Improved high dose flu vaccine for seniors”

French court hands down a ludicrous decision about Gardasil

Marie-Oceane-Bourguignon-gardasil-France-lawsuiteA few months ago, I covered a story about a French teenager who had filed a lawsuit against a French vaccine manufacturer, Sanofi Pasteur (but the patents and trademarks are owned by Merck), along with French health regulators. The lawsuit claimed that side-effects from the HPV quadrivalent vaccine, known as Gardasil (or Silgard), induced multiple sclerosis (MS), a neurological disease that results from inflammation of neurons, in a teenage girl.

As with most of these antivaccination stories and tropes, I analyze them, debunk them, and then move on. I didn’t even bother check up to see if there was a legal decision, mainly because my French reading skills barely go beyond reading a menu and ordering a croque-monsieur at a sidewalk café in Lyon (headquarters of Sanofi Pasteur). But mostly, I just assumed it was one of those silly stories where the antivaccination cult tries to make a mountain out of a tiny pebble on the beach.

Well, I misjudged the desperation of the antivaccination world. Around 8 months ago, the court actually did hand down a decision about this case, but recently the vaccine fear mongering, anti-science websites are starting to push the story. I have no clue why these vaccine refusers are pushing this story eight months later, but it’s probably because they are desperate for anything that makes them relevant, given how irrelevant most of their ideas can be. Continue reading “French court hands down a ludicrous decision about Gardasil”