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Home » COVID-19 vaccine during pregnancy – the CDC now recommends it

COVID-19 vaccine during pregnancy – the CDC now recommends it

The CDC just announced that it recommends the COVID-19 vaccine during pregnancy to protect the health of the mother and the developing fetus. The CDC stated that there are “no safety concerns” among women in their third trimester and for their newborn babies.

Despite the claims of COVID-19 deniers everywhere, the disease is dangerous and can cause both short- and long-term harm to anyone, and that means pregnant persons and their newborn babies. That’s why the COVID-19 vaccine is so important.

Let’s take a look at what the CDC said and why pregnant persons should get the COVID-19 vaccine.

COVID-19 vaccine and pregnancy – the research

The CDC recommendation was based on a study just published in the New England Journal of Medicine on 21 April 2021. The researchers used data compiled from 14 December 2020 through 28 February 2021 using data from the “v-safe after vaccination health checker” online surveillance system, the v-safe pregnancy registry, and the Vaccine Adverse Event Reporting System (VAERS) to study the initial safety of the COVID-19 mRNA vaccines from Pfizer and Moderna during pregnancy.

A total of 35,691 v-safe participants, aged 16-54, were identified as pregnant. The researchers found that injection site pain was reported more frequently among pregnant individuals than nonpregnant persons. Headache, myalgia, chills, and fever were reported less frequently among pregnant women who received the vaccine.

Among the 3958 participants enrolled in the v-safe pregnancy registry:

  • 827 had a completed pregnancy.
  • 104 of those (12.6%) had a pregnancy loss The published incidence of spontaneous abortion, irrespective of vaccination status, is between 10-26%,
  • Among live-birth infants, 9.4% were preterm (compared to a published 8-15% incidence), 3.2% were small size for gestational age (compared to published 3.5% incidence), and 2.2% had congenital anomalies (compared to a published 3% incidence).
COVID-19 vaccine pregnancy

The researchers also examined 221 VAERS reports that involved COVID-19 vaccines during pregnancy:

  • 155 (70.1%) involved non-pregnancy-specific adverse events.
  • 66 (29.9%) involved pregnant-or neonatal-specific adverse events.

I know that this is often lost on some people, but dumpster diving into the VAERS database can’t tell us much beyond very large safety signals. Also, these numbers do not represent every pregnancy where the COVID-19 vaccine was given, so the percentages don’t represent anything useful.

As it says on the VAERS website:

When evaluating data from VAERS, it is important to note that for any reported event, no cause-and-effect relationship has been established. Reports of all possible associations between vaccines and adverse events (possible side effects) are filed in VAERS. Therefore, VAERS collects data on any adverse event following vaccination, be it coincidental or truly caused by a vaccine. The report of an adverse event to VAERS is not documentation that a vaccine caused the event.

In other words, VAERS has only marginal usefulness to this analysis, and yet, it still doesn’t provide any safety signals for receiving the mRNA COVID-19 vaccine during pregnancy.


The dangers of COVID-19 during pregnancy indicate that getting the vaccine is one of the most important things that can be done to protect the pregnant person and their developing baby. Knowing that the vaccine is extremely safe during pregnancy should help anyone on the fence to feel comfortable that they are doing the right thing for themselves and their baby.

COVID-19 vaccine pregnancy
Photo by Spencer Davis on Unsplash


  • Shimabukuro TT, Kim SY, Myers TR, Moro PL, Oduyebo T, Panagiotakopoulos L, Marquez PL, Olson CK, Liu R, Chang KT, Ellington SR, Burkel VK, Smoots AN, Green CJ, Licata C, Zhang BC, Alimchandani M, Mba-Jonas A, Martin SW, Gee JM, Meaney-Delman DM; CDC v-safe COVID-19 Pregnancy Registry Team. Preliminary Findings of mRNA Covid-19 Vaccine Safety in Pregnant Persons. N Engl J Med. 2021 Jun 17;384(24):2273-2282. doi: 10.1056/NEJMoa2104983. Epub 2021 Apr 21. Erratum in: N Engl J Med. 2021 Oct 14;385(16):1536. PMID: 33882218; PMCID: PMC8117969.
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