COVID-19 vaccine candidates in phase 3 clinical trials – the official list

COVID-19 vaccine candidates
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Keeping up with COVID-19 vaccine candidates in clinical trials has gotten out of hand, so keeping up with these clinical trials have become almost impossible. For brevity, I have made the editorial decision to update this list to include just those vaccines in phase 3 clinical trials, which means that they are within the final stages of clinical assessment. 

Recently, the World Health Organization (WHO) has listed over 200 COVID19 vaccine candidates, which is amazing, but it is still too difficult to tell which ones will be successful or not without reviewing the actual data. Just because it’s in a phase 3 trial does not mean it will work.

Right now, there are nearly 50 COVID-19 vaccine candidates in phase 1, 2, or 3 clinical trials – this article will only focus on those in phase 3. 

Continue reading “COVID-19 vaccine candidates in phase 3 clinical trials – the official list”


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Pfizer COVID-19 vaccine news – should we pump the brakes just a bit?

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Recently, we saw a lot of news about the Pfizer COVID-19 vaccine –  it seemed to show about a 90% effectiveness in preventing the disease. This is potentially good news in preventing the spread of this disease because alternatives like herd immunity is a disastrous form of genocide.

But, what does this news actually mean? Does it imply that the world is saved, and soon we can eschew masks and social distancing? Does that mean the pandemic will come to an end?

We need to know if the COVID-19 vaccine actually does what Pfizer claims. We need to know if it is safe. And we need to know when the vast majority of people can receive the vaccine. When we know all of that, we can then see the light at the end of the tunnel for this deadly pandemic.

Let’s take a skeptical look at the Pfizer COVID-19 vaccine along with what it may mean to the world. I’m writing this in the form of several questions that I have with the answers as I know them. 

Continue reading “Pfizer COVID-19 vaccine news – should we pump the brakes just a bit?”


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University of California flu vaccine order – anti-vaxxers court challenge

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This article regarding the University of California flu vaccine executive order, and a subsequent anti-vaccine activist court challenge, was written by Dorit Rubinstein Reiss, Professor of Law at the University of California Hastings College of the Law (San Francisco, CA), who is a frequent contributor to this and many other blogs, providing in-depth, and intellectually stimulating, articles about vaccines, medical issues, social policy, and the law.

Professor Reiss writes extensively in law journals about the social and legal policies of vaccination. Additionally, Reiss is also a member of the Parent Advisory Board of Voices for Vaccines, a parent-led organization that supports and advocates for on-time vaccination and the reduction of vaccine-preventable disease.

An anti-vaccine organization brought a lawsuit against the University of California’s Executive Order “strongly recommending” flu vaccines for most students, faculty, and staff and mandating it for a specific sub-set. With one possible exception that I am less familiar with, but that the University responded strongly to, the complaint’s claims are unfounded and should be dismissed. Continue reading “University of California flu vaccine order – anti-vaxxers court challenge”


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FDA approved remdesivir for coronavirus – what this means for a vaccine

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On 22 October 2020, the FDA approved remdesivir from Gilead Sciences to treat COVID-19. Remdesivir is a broad-spectrum antiviral that has shown some effect in treating the novel coronavirus.

However, does this mean that the FDA approval of the drug is supported by good science? As I’ve written previously regarding rushed approvals of a potential COVID-19 vaccine, we should be concerned that the FDA has become politicized to approve COVID-19 drugs to make Donald Trump look good.

I think there’s evidence that the FDA-approved remdesivir was rushed and that the evidence supporting its use in COVID-19 treatment may be vastly overstated. Continue reading “FDA approved remdesivir for coronavirus – what this means for a vaccine”


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Governor Newsom’s COVID-19 emergency powers limited by California court

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This article about a California court decision regarding Gov. Gavin Newsom’s COVID-19 emergency powers was written by Dorit Rubinstein Reiss, Professor of Law at the University of California Hastings College of the Law (San Francisco, CA), who is a frequent contributor to this and many other blogs, providing in-depth, and intellectually stimulating, articles about vaccines, medical issues, social policy, and the law.

Professor Reiss writes extensively in law journals about the social and legal policies of vaccination. Additionally, Reiss is also a member of the Parent Advisory Board of Voices for Vaccines, a parent-led organization that supports and advocates for on-time vaccination and the reduction of vaccine-preventable disease. She is also a member of the Vaccines Working Group on Ethics and Policy.

On November 2, 2020, Judge Sarah E. Heckman ruled that the Governor’s power under the California Emergency Services Act (CESA) only included the power to suspend statutes, not to change them via executive order. While the decision clearly limits the Governor’s power to act in an emergency and raises questions about the validity of some of the Governor’s COVID-19 orders, it does not affect his order about the election that was the basis for the lawsuit, nor would it, for example, overturn California’s face covering mandate and other restrictions not issued under CESA.

It is appropriate for the judiciary to address the constitutional limits on actions by the other branches, and it’s not a bad thing to limit the powers of the governor, even in an emergency. But the narrow construction of the Governor’s power to act in an emergency under the constitution is concerning. Continue reading “Governor Newsom’s COVID-19 emergency powers limited by California court”


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Connecticut court supports masks in schools – rejects emergency injunction

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This article about a Connecticut court decision regarding masks in schools was written by Dorit Rubinstein Reiss, Professor of Law at the University of California Hastings College of the Law (San Francisco, CA), who is a frequent contributor to this and many other blogs, providing in-depth, and intellectually stimulating, articles about vaccines, medical issues, social policy, and the law.

Professor Reiss writes extensively in law journals about the social and legal policies of vaccination. Additionally, Reiss is also a member of the Parent Advisory Board of Voices for Vaccines, a parent-led organization that supports and advocates for on-time vaccination and the reduction of vaccine-preventable disease. She is also a member of the Vaccines Working Group on Ethics and Policy.

On November 2, 2020, Judge J. Moukawsher of the superior court in Hartford District, Connecticut denied the request that children do not wear masks while attending school. The Connecticut Freedom Alliance, LLC sought an emergency injunction stopping Connecticut’s Department of Education’s order that Connecticut school children wear masks. Continue reading “Connecticut court supports masks in schools – rejects emergency injunction”


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Pro-science Joe Biden – he deserves our support for President

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In case you’re living under a rock and reading this, the United States will choose either pro-science Joe Biden or science-denying Donald Trump to be our next president. There are a lot of reasons to support former Vice President Biden over Trump, but the biggest one for me is that he’s pro-science.

Science matters. And it matters more than just climate change, vaccines, COVID-19 pandemic, and many other issues that are critical to the world these days. It is also relevant to healthcare, women’s health, abortion, and competitiveness in today’s world.

I know that none of you who read this blog will be surprised that I give my strongest endorsement of the pro-science Joe Biden over that Nazi Republican Donald Trump. But let me show where Biden and science are sympatico with mine. And hopefully, yours. Continue reading “Pro-science Joe Biden – he deserves our support for President”


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Flu vaccine and COVID-19 infections – some evidence it might lower risk

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Recently, I have been discussing the flu vaccine and COVID-19 infections. First, I debunked anti-vaccine myths. Second, I explained that the seasonal flu vaccine might be helpful in improving outcomes for patients who contract the coronavirus.

However, at that time, I wanted to make it clear that:

Once again, I am not making any claim that the seasonal flu vaccine will prevent a coronavirus infection. It’s just about comorbidities, that is, other health conditions that increase one’s risk for dangerous outcomes from the disease.

Because COVID-19 is a respiratory disease, anything that weakens the respiratory system could (and again, we don’t have solid information on the pathophysiology and comorbidities for the disease) lead to a worse course for the disease. And that would include a higher risk of mortality.

The flu vaccine can reduce the risk of one coronavirus comorbidity since the flu is a respiratory disease. So, the flu vaccine isn’t going to help reduce your risk of coronavirus infection, but it will reduce your risk of complications, including death, from COVID-19.

In addition, preventing the flu may help to reduce hospitalizations and ICU admissions, allowing for more capacity for patients who have contracted COVID-19.

But again, I assumed that the flu vaccine would have little effectiveness against SARS-CoV-2, the virus that causes COVID-19. This seemed biologically plausible because, as opposed to what Donald Trump claims, the flu virus and coronavirus are vastly different organisms. The two viruses are actually in two different phyla, meaning that the influenza virus and coronavirus are as closely related as a human is to a lobster. 

There appeared to be no scientifically supported reason to believe that the flu vaccine actually prevents COVID-19. However, there seems to be some intriguing, preliminary, and potentially convincing evidence that the flu vaccine may have some effect on the risk of COVID-19. Continue reading “Flu vaccine and COVID-19 infections – some evidence it might lower risk”


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Flu vaccine deniers – the annual epic rant from Dr. Mark Crislip

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Since we’re entering the 2020-21 flu season, it’s time for the annual epic rant from Dr. Mark Crislip about flu vaccine deniers. No, Dr. Crislip does not write a new one each year, I just republish it every year, because it still makes me laugh. And each year I know there is someone out there who will also love re-reading it for fun. Or maybe it’s your first time.

This diatribe is about “Dumb Ass” healthcare workers who invent flu vaccine fallacies, tropes, and myths in an effort to justify their belief that the flu vaccine is dangerous, useless, or whatever else that hits their science-denying brain.

Dr. Crislip’s humorous compilation of these flu vaccine myths, which were originally published in A Budget of Dumb Asses, describes the different types of flu vaccine deniers among healthcare worker Dumb Asses.

Any nurse, pharmacist, therapist, physician, or surgeon that are flu vaccine deniers by using pseudoscientific nonsense about the vaccine rather than protecting their patients and themselves is appalling. 

Of course, flu vaccine deniers aren’t just healthcare workers. I’m sure you know neighbors, friends, family, and even fellow vaccine supporters who are flu vaccine deniers. And they rely on the same ridiculous myths as healthcare workers.

These flu vaccine deniers believe that the flu vaccine is not necessary because the disease is not dangerous. Nothing could be further from the truth, especially in the world of COVID-19, where the flu vaccine may actually provide benefits to those who contract the coronavirus.

 

During the 2019-2020 flu season, 194 American children died of the flu. But, there’s more:

  • 39 – 56 million Americans contracted the flu
  • 18 – 26 million of those had a medical visit because of the flu
  • 410 – 740 thousand of those had to be hospitalized as an inpatient
  • Finally, 24,000 – 62,000 died
  • Worldwide, it is estimated that there will be approximately 290-650 thousand deaths. 

We are getting started with this new flu season, hopefully by wearing masks and social distancing, which along with the flu vaccine might make this an “easy” year for the flu. Except, you know what’s going on with the world and masks.

If you think you can prevent or cure the flu with vitamin C, echinacea, or bone broth (yes, it’s a thing), they don’t work. You are not going to be able to boost your immune system to destroy the flu virus unless you get vaccinated.

We’ve dispensed with many of the cherished flu vaccine fallacies of the anti-vaccine religion. Moreover, many studies have shown that getting the flu vaccine can improve health outcomes.

Too many people, including healthcare workers, are flu vaccine deniers. 

Continue reading “Flu vaccine deniers – the annual epic rant from Dr. Mark Crislip”


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Flu treatment quackery – it is all woo, so get your influenza vaccine

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It’s that time of year when we are bombarded by flu treatment quackery from “immune-boosting” miracle supplements to junk that “cures” every single virus known to medical science. During this world of the coronavirus pandemic, it seems to be even louder

This article will attempt to debunk the myths of flu treatments such as “boosting the immune system,” magical supplements, and other nonsense involved with the world of flu treatment pseudoscience.

The one way to prevent the flu, other than hiding in a bubble during the winter (which may be a good thing with the COVID-19 pandemic), is the seasonal flu vaccine. But that’s not a treatment, it prevents the flu.

Continue reading “Flu treatment quackery – it is all woo, so get your influenza vaccine”


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