How to prevent cancer in 12 easy steps–OK, not that easy

I have railed against charlatans who claim that they have the easy way to prevent or cure cancer. Generally, these snake oil salesmen try to convince you that they have some miraculous food, supplement, spiritual energy, and on and on, that can either kill cancer in its tracks. Or keep them from even growing in your body. But their claims are nearly always absent real compelling scientific evidence.

Like the trope supplements preventing cancer. They don’t. And that’s been shown in study after study after study after study (yeah, I could go on for awhile).

Or like avoiding GMO containing foods prevents cancer. Again, studies show that GMO foods have no effect on cancers. Oh, one more thing–bananas don’t have tumor necrosis factor, and the yellow fruit can’t prevent or cure cancer (but that doesn’t mean that they aren’t delicious).

Despite the absolute lack of evidence that supplements, kale, bananas, or drinking the pure waters of a glacial fed stream (which may not be an option with climate change), there are some things that can be done to reduce your risk (see what I did there–no absolutes, just management of risks) of cancer.

How to prevent cancer has been codified byThe World Health Organization (WHO) into 12 steps (no, not that debunked one) that is called the European Code Against Cancer.

Let’s take a look at cancer and the evidence-based ideas about cancer prevention.

What is cancer?

Simply, cancer is a disease in which cells of the body grow in an uncontrolled way, forming a tumor that may spread to different parts of the body. There are around 250 types of cancer, though the exact number is not precisely known, since some cancers may be related to others, or may not be cancers at all. But 250 is a good average.

All cancers are caused by mutations in the DNA of cells in the body. Most of the time, cells deal with these mutations by “fixing” the DNA. Or the mutation is so serious that the cell simply dies (it’s really one cell, and cells die in your body constantly). If the mutated cell lives and divides, the body has immune defenses against most mutations–so it’s gone before you would even know that it’s there.

Technically, with 46-68 trillions of cells in the average human body, even if a cell mutation is extraordinarily rare, the law of large numbers means that you could have literally hundreds of cancer cells living in your body, dying naturally, or being destroyed by the immune system, or not causing any problems at all. There are just so many cells in the body, and the cellular replication mechanism being slightly less than perfect, mutations will happen.

The odds against a cancer growing is even worse than I’m stating. For a cancer to survive from a single cell, to a mass of cells, requires nutrition (forcing the body to feed it with blood vessels). To do that, it needs another mutation of the cell. Then it needs to grow unrestricted by the normal growth control systems of the body–another couple of specific mutations. The cancer also needs to hide from the immune system, more mutations.

I could go on and on, but it could take up to 10 individual and correctly placed mutations for a cell to become a cancer. Again, with trillions of cells, it becomes mathematically possible, but very hard to do. Let’s look at cancer from a strictly mathematical point of view–it’s really really really really really rare. To pile up 4 or more mutations that all are advantageous to the cancer cell is almost unimaginable.

cancer-mutation-graphic

However, outside agents, like infections, tobacco smoke, radiation (more broadly than just radioactive energy, but ultraviolet and other types of radiation), and human physiology can cause (or allow to cause) so many mutations that eventually one leads to an increase in the number of mutated cells, then a growing viable cancer.

 

Cancer is rare

Cancer is generally just a random event, a non-preventable risk, unless an outside force causes an increase in such risk. This is why supplements or diet (other than generally consuming a diet that supplies your nutritional needs) really are nonsense in preventing cancers.

Again, we’re talking about 46-68 trillion cells in your body, some of which aren’t easily accessed, so it’s impossible to consume enough supplements to reach a concentration in all cells in the body that it would have a clinical effect (though it’s doubtful that it would even have an effect then). And the cellular mutations can’t be stopped, nor can they be reversed, by a supplement. Again, it’s essentially a random mutation and more times than not it’s fixed by the cell itself.

The USA’s National Cancer Institute lists about 150 different cancers, but they don’t list some of the very rare cancers. In fact, of those 150, really twelve make up the bulk of cancers in the world. Because people generally live longer these days, the risk (remember, it’s risk, not a yes or no) of cancer is higher–the law of big numbers gets bigger with more years of those trillions of cells have a chance at that random mutation.

Furthermore, as one ages, the cellular DNA repair system doesn’t work as efficiently. So, the risk of cancer slowly increases without any outside forces–to lower that risk is the point of the WHO cancer code.

 

Are more people dying of cancer?

The simple answer is no.

More people die of cancer today, just because the population is larger and older. But the actual incidence, that is the number of people who get cancer in a fixed population, has dropped substantially. In a recent study, the authors looked at mortality rates over a 60 year period of time, and they found that:

[infobox icon=”quote-left”][Cancer] mortality has been systematically decreasing among younger individuals for many decades. … the cancer mortality rates for 30 to 59 year olds born between 1945 and 1954 was 29% lower than for people of the same age born three decades earlier. … substantial changes in cancer mortality risk across the life span have been developing over the past half century in the United States. … this analysis suggests that efforts in prevention, early detection, and/or treatment have significantly affected our society’s experience of cancer risk.[/infobox]

In other words, despite claims made by some pseudoscience pushers, the actual cancer mortality rate has dropped substantially. Anecdotally, people think that cancer is more prevalent, because we have contact with more people who are older than the same population 30 years ago. We used to die of other things, infectious diseases, malnutrition, pollution, and maybe wolf or bear attacks, well before a cancer could arise in our bodies. Today, we all live relatively safe lives, so when we hit our 50’s and 60’s, cancer becomes more apparent to everyone.

There’s something else in the lower rate of cancer (and cancer mortality). It’s that the collective will of scientific research in treating or preventing cancer has brought about significant changes. We know that smoking and sunbathing have a direct causal link to some cancers. We know how to aggressively treat cancers to the point of moving some cancers from being death sentences to being treated and managed to great success. .

Let’s make this clear. Despite what is claimed and what is believed, the absolute rate of cancer has dropped. The mortality rate from cancer has dropped substantially. It would be ridiculous for me to think that cancer can be cured (again, there are maybe 200 cancers, all of them with different physiologies, causes, and treatments), but modern medicine is winning the war.

But there are things you can do to reduce your risk of cancer (there’s no way to absolutely prevent it–remember, it’s a random event).

 

healthy-weight

How to prevent cancer – 12 steps

  1. Stop smoking tobacco. This is the number one way to reduce your risk of cancer–smoking causes lung cancer, which is the #1 cancer killer in the US and Europe. In fact, smokers are 15-30X more likely to contract and die of lung cancer than non-smokers. This isn’t something that we’ve known just for a couple of years, but since before the 1950’s.And it’s not just smoking tobacco that increases the risk of cancer–using it in other forms, such as smokeless tobacco can contribute to significantly higher risks of cancer. But the good news is that the sooner one quits using tobacco products the better the long term prognosis. Studies have shown that smokers who quit at about age 30 reduce their chance of dying prematurely from smoking-related diseases by more than 90 percent.
  2. Avoid second-hand smoke. Even if you avoid smoking personally, second-hand smoke has nearly the same health risk, depending on the frequency of encountering smoke. In the USA, inhaling cigarette smoke, unless one is a smoker, has become relatively rare. But in Europe, even with official bans on smoking, the risk of encountering second-hand smoke can vary by country and location from 31-90%.
  3. Maintain a healthy weight. Keeping one’s BMI between 18.5 and 24.9 kg/sq m can lead to an 18% lower risk of cancer. Scientifically, it is possible that other confounding factors, say high fat diet or smoking, may lead to the higher risk being associated with obesity, but the evidence seems to be show a possible causal relationship. Besides, obesity leads to a much higher risk of heart disease, joint problems, and dozens of other medical issues.
  4. Be physically active. Closely related to #3. Being physically active helps maintain a healthy weight.
  5. Eat a healthy diet. No, this does not mean that eating kale and soy milkshake is going to reduce the risk of any cancer. However, as WHO states, eating a diet filled with whole grains, fruits and vegetable, while avoiding high fat and high sugar foods will help with #3. There’s no solid evidence that a particular diet will reduce the risk of cancer, BUT a healthy diet can lead to weight loss and maintaining the appropriate BMI.
  6. Avoiding alcohol. Alcohol, even moderate amounts, leads to a significant increase in risk of certain cancers. In fact, alcohol consumption causes around 3% of cancer deaths in the USA. And not to repeat a point–reduced alcohol consumption can lead to weight loss–to maintain that healthy weight.
  7. Avoid the sun (and UV tanning beds). Ultraviolet (UV) light, mostly sunlight, can damage surface skin cells leading to some very serious cancers. Although one form of UV light, UVB, is necessary for the production  of vitamin D, an essential nutrient, excessive UVB can lead to permanent damage to cells. Getting vitamin D through supplements or foods is probably healthier than sunlight.
  8. Avoid pollutants. Some believe that all “chemicals” are bad, and they aren’t, there really are some that are known carcinogens and should be avoided. The current “chemophobia” of many people is borderline ridiculous, because even known carcinogenic chemicals can only increase the risk of cancer at certain levels, meaning they could be safe in extremely low amounts. It’s all about the dose. It’s impossible to avoid all man-made and natural chemicals (there are more so called natural substances that are carcinogenic than humans could possibly invent), but avoiding polluted water and air, or being careful in a workplace that has a lot of chemicals, will help manage the risk. Remember, the theory (from a scientific perspective) that cancers arise from frequent mutations means that the risk increases as the number of mutations increase. The world isn’t perfect, but it’s not either no chemicals or “we’re all going to die of cancer” type of false dichotomy.
  9. Avoid radiation. This risk is really just radon gas, although individuals in some careers may be exposed to other types of radioactive energy, an invisible radioactive gas that is found in many homes in certain geological areas. It can be easily detected, and easily removed from the air, but it does require testing. Many people would not rent or buy a home without having it thoroughly tested for radon gas–I wouldn’t.
  10. Breastfeed your baby. Women who breastfeed their babies for extended periods of time reduce their risk of breast cancer in later life when compared to women who do not breastfeed. In fact, the reduction in risk of breast cancer is about 4% for every 12 months of breastfeeding (which can be summed up over more than just one baby). This reduction in risk is above and beyond the reduced risk of breast cancers from having a baby.
  11.  Get your vaccinations. It’s ironic that the pseudoscience pushers are solidly antivaccine, yet promote unfounded and unsupported “cancer preventions”. Yet two vaccines, for hepatitis B and HPV, actually prevent more cancer than drinking 100 kale shakes. The hepatitis B vaccine has caused a 96% decrease in hepatitis B infections, which is related to over 50% of the cases of a liver cancer, hepatocellular carcinoma.
    The HPV vaccine, known as Gardasil, Silgard, or Cervarix, blocks infection of the human papillomavirus which is linked to several types of terrible cancers. Despite the myths, the HPV vaccine is incredibly safe, possibly the safest vaccine of all vaccines (which are all extremely safe) and demonstrably effective in reducing HPV infection and related cancers. These vaccines are some of the most effective methods to prevent cancers. Seriously, one could swallow hundreds or thousands of supplements, and these vaccines will actually do more to prevent cancer than those overpriced supplements will ever do. And yes, the scientific evidence supports that statement.
  12. Get screened for cancer.  There are screenings for a huge number of cancers. One can get a colonoscopy for hard to detect intestinal cancers. There are simple screenings for cervical and prostate cancer. There is imaging for small tumors on internal organs. There are blood tests for others. Yes, getting a colonoscopy, if you’re age-appropriate, is not easy. But it’s not dangerous, and it can detect cancer very early, before it kills. Once again, screening is much more effective than the mythical miracle kale shake.

stop-smoking

The TL;DR version

  • Preventing and treating cancer is not as easy as the “natural food and supplement” people claim. It’s because they oversimplify and understate the biology of cancer. They want people to think “take this pill, don’t worry any more.”
  • Cancer incidence and mortality are dropping. Modern, science-based medicine is the cause.
  • Stop smoking.
  • Lose weight.
  • Get out of the sun.
  • Don’t drink carcinogens.
  • Make sure your house has no radon.
  • Breastfeed your baby (if you’re a woman of course) for as long as possible.
  • Get the hepatitis B and HPV vaccines.
  • Get regular screenings for cancer.

I know. It’s not really that easy, probably not as easy as downing $20 of supplements that will just be passed in the urine. But if any of you really want to reduce your risk of cancer, then you’ll have to do this. Or just drink your kale shakes. That’ll at least make you lose weight.

Editor’s note: This article was originally published in October 2014. It has been revised and updated to fix some SEO issues.

 

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The Original Skeptical Raptor
Chief Executive Officer at SkepticalRaptor
Lifetime lover of science, especially biomedical research. Spent years in academics, business development, research, and traveling the world shilling for Big Pharma. I love sports, mostly college basketball and football, hockey, and baseball. I enjoy great food and intelligent conversation. And a delicious morning coffee!