BCG lung cancer vaccine? The avian dinosaur analyzes the clinical trial

lung cancer vaccine

Recently, a paper was published which described a potential lung cancer vaccine. Interestingly, it’s not a novel vaccine, but it’s the BCG vaccine that’s been around for nearly 100 years.

Unless you are really into vaccines or had a typical education as a physician or nurse, you probably don’t know much about the BCG vaccine, because it’s not a typical part of the  CDC immunization schedule for either adults or children. 

So, let’s talk about this vaccine, and its use as a lung cancer vaccine. Continue reading “BCG lung cancer vaccine? The avian dinosaur analyzes the clinical trial”

BCG vaccine is priced too low – now, shortage for bladder cancer

bcg vaccine

You probably don’t know much about the BCG vaccine, because it isn’t used much these days. And no, it’s not one of the vaccines on the CDC immunization schedule for either adults or children. 

The Bacillus Calmette-Guerin vaccine, or BCG vaccine, was initially developed to prevent tuberculosis. The disease is caused by bacteria called Mycobacterium tuberculosis. The bacteria usually attack the lungs, but they can also damage other parts of the body. Tuberculosis is treatable with advanced medicines, but it takes a long time and can be expensive. Without treatment, the patient will die.

So, why does it matter that the BCG vaccine is priced too low or that we have a shortage of it? Well, it has a couple of important uses (one current, and one potential) that has driven demand for the vaccine. And it’s not because there’s a sudden worldwide epidemic of tuberculosis. Continue reading “BCG vaccine is priced too low – now, shortage for bladder cancer”

Reverse type 1 diabetes mellitus with BCG vaccine – promising results

reverse type 1 diabetes

A clinical trial that examined the potential of the bacillus Calmette-Guerin vaccine, or BCG vaccine, to reverse even advanced type 1 diabetes mellitus was recently published in a Nature journal. In addition, researchers proposed a possible mechanism describing how the BCG vaccine may enhance the immune system and could stop and reverse the damage that leads to diabetes. But does this constitute evidence that this vaccine can really reverse type 1 diabetes? Spoiler alert – I’m not fully convinced, but my interest is piqued.

The BCG vaccine was initially developed to prevent tuberculosis. It is one of the oldest vaccines available on the market, first used in 1921 (pdf). With the successful eradication of tuberculosis in many countries, the vaccine isn’t used very much anymore, except in countries with endemic tuberculosis.

Let’s take a look at what we know about diabetes, how the BCG vaccine might be able to reverse type 1 diabetes mellitus, and what the new article reports. Continue reading “Reverse type 1 diabetes mellitus with BCG vaccine – promising results”

BCG vaccine – can it reverse type 1 diabetes mellitus?

bcg vaccine

Initial results from a clinical trial that is testing the ability of the bacillus Calmette-Guerin, or BCG vaccine, to reverse even advanced type 1 diabetes mellitus. In addition, researchers seem to have identified how the vaccine enhances the immune system, stopping and reversing the damage that leads to diabetes.

The BCG vaccine was developed to prevent tuberculosis. It is one of the oldest vaccines available on the market, first used in 1921 (pdf). With the successful eradication of tuberculosis in many countries, the vaccine isn’t used very much anymore, except in countries with endemic tuberculosis.

Although the results are very preliminary, the BCG vaccine may very well lead to an effective “cure” for type 1 diabetes. This will be an exciting development for what is now considered to be an incurable disease.

Let’s take a look at what we know about diabetes and how the BCG vaccine is able to reverse the disease. Continue reading “BCG vaccine – can it reverse type 1 diabetes mellitus?”