Antidepressants cause autism – another red flag

Antidepressants cause autism

The headlines are screaming again, ANTIDEPRESSANTS CAUSE AUTISM !!!!!!!!!!!!! (approximate average number of exclamation marks per article). Of course, a critical analysis of the the underlying study that caused the headlines is more nuanced and may not say what you think it says.

Autism spectrum disorder is a complex range of conditions classified as neurodevelopmental disorders by the American Psychiatric Association, which is described in detail in the Diagnostic and Statistical Manual of Mental Disorders 5th edition (DSM-5).

The DSM-5 redefined autism spectrum disorder to encompass diagnoses of autismAsperger syndromepervasive developmental disorder not otherwise specified (PDD-NOS), and childhood disintegrative disorder. Generally, symptoms of these disorders include social deficits and communication difficulties, stereotyped or repetitive behaviors and interests, sensory issues, and in some cases, cognitive delays.

The scientific consensus for the causes of autism has centered on genetic factors, generally several genes. This hasn’t stopped a whole host of claims as to what causes autism. Emily Willingham wrote an article a few years ago with the title, This just in: Being alive linked to autism, in which she lists 30 recent claims of what causes autism. It would be funny, if it weren’t so sad.

Of course, we cannot overlook the old canard that vaccines cause autism. Which is about as untrue as a claim can be in science.

So what about this new claim about antidepressants and autism spectrum disorder? It’s based on a study just published in JAMA Pediatrics, a relatively high impact factor (approximately 7.148) and selective peer-reviewed journal.

The results from the may be significant, but possibly a critical analysis of the article will give us a different perspective. Continue reading “Antidepressants cause autism – another red flag”

Flu during pregnancy is associated with bipolar disorder in children

pregnant-flu-vaccineA recent article published in a leading psychiatry journal, JAMA Psychiatry, has shown that pregnant mothers’ exposure to the influenza (flu) was associated with a nearly 4X increase in risk to their child eventually developing bipolar disorder in adulthood. These findings add to mounting evidence of possible shared underlying causes and illness processes with schizophrenia, which some studies have also linked to prenatal exposure to influenza. Bipolar disorder, historically called manic depressive disorder, is a mood disorder where the sufferer can experience episodes of a frenzied state known as mania (or hypomania), typically alternating with episodes of depression. It can be treated with medications and psychotherapy (especially cognitive therapy), but more difficult cases require the individual to be voluntarily or involuntarily institutionalized until the mood changes can be reduced or eliminated.

Continue reading “Flu during pregnancy is associated with bipolar disorder in children”