The headlines are screaming again, ANTIDEPRESSANTS CAUSE AUTISM !!!!!!!!!!!!! (approximate average number of exclamation marks per article). Of course, a critical analysis of the the underlying study that caused the headlines is more nuanced and may not say what you think it says.
Autism spectrum disorder is a complex range of conditions classified as neurodevelopmental disorders by the American Psychiatric Association, which is described in detail in the Diagnostic and Statistical Manual of Mental Disorders 5th edition (DSM-5).
The DSM-5 redefined autism spectrum disorder to encompass diagnoses of autism, Asperger syndrome, pervasive developmental disorder not otherwise specified (PDD-NOS), and childhood disintegrative disorder. Generally, symptoms of these disorders include social deficits and communication difficulties, stereotyped or repetitive behaviors and interests, sensory issues, and in some cases, cognitive delays.
The scientific consensus for the causes of autism has centered on genetic factors, generally several genes. This hasn’t stopped a whole host of claims as to what causes autism. Emily Willingham wrote an article a few years ago with the title, This just in: Being alive linked to autism, in which she lists 30 recent claims of what causes autism. It would be funny, if it weren’t so sad.
Of course, we cannot overlook the old canard that vaccines cause autism. Which is about as untrue as a claim can be in science.
So what about this new claim about antidepressants and autism spectrum disorder? It’s based on a study just published in JAMA Pediatrics, a relatively high impact factor (approximately 7.148) and selective peer-reviewed journal.
The results from the may be significant, but possibly a critical analysis of the article will give us a different perspective. Continue reading “Antidepressants cause autism – another red flag”