Shingles, a reactivated form of the chickenpox virus, is a painful rash that afflicts many people decades after the initial chickenpox infection. Now, we have data that shingles increase heart attacks (myocardial infarction) and strokes. This is more evidence that we need to end chickenpox with the chickenpox vaccine, and reduce the risk of shingles in those who have had chickenpox with the shingles vaccine.
Let’s take a look at shingles and this new study. Continue reading “Shingles increase heart attacks – time for the vaccine”
There are a lot of nuanced facts and evidence about vaccines. The so-called “pro-vaccine” crowd looks at the body of evidence, then concludes that it saves children’s lives by stopping vaccine preventable diseases. The “anti-vaccine” side seems to rely on anecdotes, cherry picking bad studies published in really bad journals, and read anti-science websites, just to support their preconceived conclusions. And now there is a lot of junk science with respect to chickenpox vaccine and shingles, much of which we need to debunk.
One of the enduring myths of the antivaccine cult is that chickenpox vaccine will increase the rate of shingles, especially in older adults. A recent published article examines chickenpox vaccine and shingles – and like everything in science, it’s the nuanced data that makes the story. Not the headlines.
Continue reading “Chickenpox vaccine and shingles – the nuanced facts”
Lest we forget, vaccines are one of the greatest medical inventions of all time. Without them, we would see cemeteries filled with children who would have died before they were even five years old. In fact, the best evidence we have tells us that vaccines prevented 200 million cases of diseases in the USA alone in the five decades since 1963.
A recent study, published in AIMS Public Health, estimates that around 200 million cases of polio, mumps, rubella, measles, adenovirus, hepatitis A and rabies have been prevented in the U.S. from 1963 through 2015 as a result of widespread vaccination. The study, authored by Leonard Hayflick and S. Jay Olshansky, two leading experts on public health and infectious diseases, also discloses that about 450,000 deaths have been avoided in the U.S during this period, although other studies put that estimate of lives saved at a much higher number.
Dr. Hayflick discovered the human cell strain, WI-38, in 1962 which was critical to the safe manufacturing of vaccines, which became widespread in 1963. According to the article, the vaccines produced from the WI-38 cell line prevented almost 4.5 billion occurrences of the diseases, and stopped them from returning to infect us. Dr. Hayflick developed the foundation that allowed the world to have relative safe and very effective tools to prevent infectious diseases.
Prior to the development of WI-38, anti-virus vaccines were grown in monkey cells, which had some issues that made many question their safety, although most of the concern appeared to be overblown. However, once the WI-38 was available, it became easier to develop and produce vaccines for many viruses.
Drs. Hayflick and Olshansky wanted to see what effect that seminal event had on public health. And the numbers were incredible. Continue reading “Vaccines prevented 200 million cases of disease in the USA from 1963 to 2015”
Generally, when I write about vaccines, it’s about protecting children’s lives from vaccine preventable diseases. That itself is a noble goal for vaccines. But in case you didn’t know, there is also a CDC schedule for adult vaccines, which is as important to adults as they are to children.
Vaccines have one purpose – to protect us and those whom we love from potentially deadly and debilitating diseases. Many of us in the blogosphere have talked about the children’s schedule a lot, often to debunk claims of people who are ignorant of science, and think that the children’s vaccine schedule is causing undue harm. Yeah our intellectually deficient president, Donald Trump, thinks he knows more than the CDC, but that’s a problem shared by many vaccine deniers.
One adult vaccine I push regularly is the flu vaccine. It protects adults, pregnant women, the elderly, children, and healthy young adults from a severe infection that hospitalizes and kills more people every year than you’d think. Because flu is not really a serious disease, in some people’s minds, a lot of people decide that they don’t need the vaccine. They’d be wrong.
Just in case you were wondering, there is more to adult vaccines than just flu vaccines. There are several other vaccines indicated for adult use, including those adults with underlying health issues like diabetes, HIV and heart disease – unfortunately, the uptake for adult vaccines is depressingly low. Let’s take at the low uptake and the recommended adult vaccines schedule.
Continue reading “Adult vaccines – the CDC wants to save adult lives too”
The varicella vaccination for chickenpox was introduced in the mid-1990’s in the USA and has been associated with substantial and statistically significant declines in incidence, hospitalizations and deaths attributable to chickenpox. Thanks to real science, more evidence supports varicella vaccine effectiveness.
Despite the beliefs of vaccine refusers, who have stated emphatically that chickenpox is not dangerous, the real complications from a varicella infection are numerous and serious:
- bleeding problems
- infection or inflammation of the brain (encephalitis, cerebellar ataxia)
- bacterial infections of the skin and soft tissues in children including Group A streptococcal infections
- blood stream infections (sepsis)
- toxic shock syndrome
- bone infections
- joint infections
Since I was born before the chicken pox vaccine, I contracted the disease, which eventually lead to encephalitis. I have vivid memories of being a five year old child and being admitted into the ER with a brain infection. It’s a memory I’d rather not have.
The anti-vaccine gang love to question the effectiveness of vaccines. But they don’t have evidence of that, whereas, I’m going to present some powerful evidence that the varicella vaccine is highly effective in preventing chickenpox.
Continue reading “Varicella vaccine effectiveness – more supporting evidence”
There are many canards propagated by the vaccine deniers to support their personal beliefs (really, denialism) about the safety and effectiveness of vaccines. One of their more popular beliefs is that vaccines didn’t end many of the deadly diseases, but improved sanitation, healthcare, nutrition or magical fairies (also known as homeopathy) ended these diseases.
There is even a subgroup of these believers who think that the CDC, historians, and everyone else is lying about the epidemics that existed prior to vaccinations–let’s call this group history deniers. They reject the scientific and historical evidence that vaccines saved lives – amazing.
So, is there scientific evidence that vaccines actually ended these epidemics? Yes there is, and it’s unequivocal. Unless you want to embrace historical revisionism, and somehow all of the health care records and epidemiological information was faked, vaccines saved lives – lots of lives. Continue reading “Vaccines saved lives – scientific evidence”
There are so many silly memes that have arisen from the vaccine deniers, most of which have been thoroughly debunked. Everything from the well-worn (and worn-out) “vaccines cause autism” fable, which I have quashed here, to the “these diseases aren’t dangerous”, which, of course, couldn’t be farther from the truth.
One of the more annoying of the tales pushed by the vaccine refusers is that vaccines aren’t tested thoroughly before being used on unsuspecting infants. I do not know where this started, or why it started, but like much in the anti-vaccination world, it really doesn’t matter. It just passes from one person to another across google, and individuals with no research background hold this particular belief as if it were the Truth™.
Not only are vaccines thoroughly tested for safety and efficacy before being marketed, they also are rigorously tested in various combinations with other vaccines. And I’m not Cherry Picking a few articles to support my point of view, unless by cherry-picking you mean I’m picking the best articles from the highest quality journals in medicine.
Continue reading “Vaccines aren’t tested – myth vs. science (updated)”
Yesterday, while researching videos and articles for my post about Stuart Scott, I ran across a video where Keith Olbermann, noted sports journalist and noted progressive pundit, was leaning on a cane while talking to Scott, who was fighting for his life against appendix cancer. I wrote a note to myself to find out the backstory.
Then Olbermann made it easy for me–on his afternoon show on ESPN2, said that he was using the cane because of an extremely severe case of shingles, sometimes known as herpes zoster. Shingles is actually caused by the chickenpox virus, Varicella zoster. If you have had the chickenpox infection, you don’t actually get cured by ridding yourself of the virus–what happens it that the zoster virus remains latent in the nerve cell bodies and other nervous system bodies. While the virus is in this latent condition, it is ignored by the immune system and there are no obvious symptoms or signs that it’s there. Continue reading “Keith Olbermann and shingles–get the vaccine”
Despite the continued social network misinformation about vaccine safety and/or effectiveness, the United States Centers for Disease Control and Prevention (CDC) has reported that the median vaccination coverage, amongst children between the age of 19-35 months was 94.7% for 2 doses of measles, mumps, and rubella (MMR) vaccine; 95.0% for varying local requirements for diphtheria, tetanus toxoid, and acellular pertussis (DTaP) vaccine; and 93.3% for 2 doses of varicella vaccine among those states with a 2-dose requirement.
The median total exemption rate was 1.8%, a difficult number to truly analyze. The CDC reported many issues like some parents get an exemption even after their children are fully or partially vaccinated, some exemptions are used as a matter of convenience because the parents forgot to vaccinated, and some states don’t report exemptions. Moreover, the CDC data indicates up to 15% of exemptions are “medical,” meaning that a child cannot receive a vaccine as a result of an establish medical contraindication.
Although these numbers fall near the 95% vaccination rate goal establish by the CDC’s Health People 2020, there is still a concern that clusters of unvaccinated or under-vaccinated children exist in many states and areas. Those locations become susceptible to outbreaks of vaccine-preventable diseases. Moreover, 26 states and DC failed to meet the 95% goal, so the disparity between vaccinated and unvaccinated groups remain large.
The research also shows that there have been no statistically significant changes in either vaccination or exemption rate from 2012-13. This is more statistical support that the antivaccination agenda is not gaining much traction across most of the USA.
Continue reading “2013-14 vaccine uptake in the USA is still high”
This article, originally published on 2 January 2014 has been updated to include more information about studies regarding chickenpox in children and its effect on rate of shingles outbreaks.
Shingles, known medically as Herpes zoster (HZ), is caused by the Varicella zoster virus (VZV), which causes chickenpox in children. After the chickenpox infection, VZV latently persists, without symptoms, in the basal ganglia including the trigeminal ganglion. For unknown reasons, VZV is reactivated from latency, and moves along sensory nerves to the endings in the skin, where it replicates causing the characteristic HZ rash, commonly called shingles.
There is no known cure for VZV, though it can be treated with antiviral medications. Although the infection presents with a rash, commonly fairly painful, it usually subsides within three to five weeks. Unfortunately, about one in five patients develop a painful condition called postherpetic neuralgia, which is often difficult to manage. Because VZV is never eliminated, after a shingles attack, VZV again becomes latent, to attack again sometime in the future. Continue reading “Why we vaccinate-shingles may increase risk of stroke”