HPV vaccine efficacy – another study shows long-term immunogenicity

HPV vaccine efficacy

As I’ve mentioned dozens of times, the anti-vaccine religion probably hates the HPV vaccine more than all others put together. They’ve invented numerous myths and tropes about the HPV vaccine, all without any foundation in science. One of these claims is that we don’t know anything about long-term HPV vaccine efficacy.

Of course, the HPV vaccine is a relatively new one, so long-term data requires us to wait for time to pass. Fortunately, we are accumulating a boatload of data that shows us that the long-term HPV vaccine efficacy is pretty strong.

And now, we have a powerful new study from Finland that shows that after 12 years post-vaccination, anti-HPV immunogenicity remains quite high. Let’s take a look. Continue reading “HPV vaccine efficacy – another study shows long-term immunogenicity”

Pandemic flu vaccine and narcolepsy–an analysis

H1N1 vaccineToday, the British Medical Journal published a retrospective study, by Elizabeth Miller, that analyzes the risk of narcolepsy in children and adolescents in England who received the 2009 A/H1N1 pandemic flu vaccine (Pandemrix) from October 2009 through mid-2010. This study followed up on the observations seen in Finland and other countries that there was some increased risk of narcolepsy in children a few months after receiving the vaccine.

As background, narcolepsy is a chronic neurological disorder caused by the brain’s inability to regulate sleep-wake cycles normally. Individuals with narcolepsy often experience daytime sleep patterns, but the disorder should not be confused with insomnia. It is not caused by a mental illness or psychological problems. It is most likely affected by a number of genetic mutations and abnormalities that affect specific biologic factors in the brain, combined with an environmental trigger during the brain’s development, such as a virus. It may also be a result of an autoimmune disorder. At this time, there is no cure for narcolepsy, but it can be successfully treated by medications and other therapies.

Roughly 70% of individuals who have narcolepsy have a comorbidity of cataplexy,  a sudden and transient episode of loss of muscle tone, often triggered by strong emotions.  Continue reading “Pandemic flu vaccine and narcolepsy–an analysis”