HPV vaccinations lagging despite strong safety and effectiveness

hpvThe CDC recently reported that only about half of US teenager girls have received the safe and effective quadrivalent HPV vaccine (HPV4), a disappointing level of vaccine uptake. Moreover, this rate hasn’t changed over the past three years, despite significant efforts to increase the awareness and effectiveness of the vaccine amongst teenagers. Even worse news in this report is that only about one-third of teenage girls have been fully immunized with all three doses.

HPV quadrivalent vaccine, also known as Gardasil (or Silgard in Europe), is marketed by Merck & Co., usually for vaccination of teenage girls (with an increasing number of boys). The vaccine prevents the transmission of certain types (pdf) of human papillomavirus (HPV), specifically types 6, 11, 16 and 18. 

HPV types 16 and 18 cause approximately 70% of cervical cancers, and caused most HPV-induced anal (95% linked to HPV), vulvar (50% linked), vaginal (65% linked), oropharyngeal (60% linked) and penile (35% linked) cancers. These cancers, mostly related to HPV, can be prevented as long as you can prevent the HPV infection from ever happening, which usually happens through genital contact, most often during vaginal and anal sex.

HPV may also be passed on during oral sex and genital-to-genital contact. HPV can be passed on between straight and same-sex partners—even when the infected partner has no signs or symptoms. Approximately 79 million Americans, most in their late teens and early 20′s, are infected with HPV, and about 14 million people become infected each year in the USA. Continue reading “HPV vaccinations lagging despite strong safety and effectiveness”

Study shows HPV vaccine lowers HPV infection risk in teen girls

conservative-HPV-vaccineHPV quadrivalent vaccine, also known as Gardasil (or Silgard in Europe), is marketed by Merck, usually for vaccination of teenage girls (with an increasing number of boys). The vaccine prevents the transmission of certain types (pdf) of human papillomavirus (HPV), specifically types 6, 11, 16 and 18. HPV types 16 and 18 cause approximately 70% of cervical cancers, and caused most HPV-induced anal (95% linked to HPV), vulvar (50% linked), vaginal (65% linked), oropharyngeal (60% linked) and penile (35% linked) cancers. These cancers, mostly related to HPV, can be prevented as long as you can prevent the HPV infection from ever happening, which usually happens through genital contact, most often during vaginal and anal sex. HPV may also be passed on during oral sex and genital-to-genital contact. HPV can be passed on between straight and same-sex partners—even when the infected partner has no signs or symptoms. Approximately 79 million Americans, most in their late teens and early 20’s, are infected with HPV, and about 14 million people become infected each year in the USA. Continue reading “Study shows HPV vaccine lowers HPV infection risk in teen girls”

Japan Health Ministry pulls recommendation for HPV vaccination

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I was going to put some snarky comment in the title like, “but wait, what about the statistics.” Because we know that this isn’t a good decision, and that the vaccine deniers will be all over it like MrAndy Wakefield’s fraudulent and retracted study claiming that vaccines cause autism. But let’s move on to what happened.

According to a English newspaper in Japan,

The health ministry decided June 14 to withdraw its recommendation for a vaccination to protect girls against cervical cancer after hundreds complained about possible side effects, including long-term pain and numbness.

The Ministry of Health, Labor and Welfare is not suspending the use of the vaccination, but it has instructed local governments not to promote the use of the medicine while studies are conducted on the matter.

So far, an estimated 3.28 million people have received the vaccination. However, 1,968 cases of possible side effects, including body pain, have been reported.

The ministry’s task force discussed 43 of those cases. However, a cause-and-effect relationship between the vaccination and the pain and numbness could not be established, so the task force members called for further studies by the ministry.

The ministry’s investigation is expected to take several months. It will then decide whether to reinstate or continue to withhold its recommendation for the vaccination.

So, the health ministry is going to withhold recommendation of the HPV vaccination because they notice 43 cases for which they couldn’t establish a causal relationship to the vaccine. In other words, 0.0013% of cases, a number so small that it’s pretty close to impossible to affix any statistical significance to it. In fact, random background “noise” (that is that some whole body pain could be expected in any random sampling of vaccinated or unvaccinated individuals) of this type of observation is as plausible as correlation (let alone causation) to the vaccine. In fact, the Health Ministry failed to provide us with data concerning the level of these side effects in the general population. Nor how soon after vaccination. Nor anything potentially useful in a scientific analysis.

What’s worse is that, according to the same article, about 2700 women in Japan die every year from HPV related cancers. So, because of complaints from the antivaccination lunatics in Japan (didn’t know they had any, but I shouldn’t be surprised), and bad statistics (43 potential cases of “body pain” out of 3,280,000 vaccinations), the Health Ministry stops recommending the vaccine. Exactly what were these people thinking?

Finally, let’s be clear here. The vaccine hasn’t been pulled from the market nor has it been outlawed; teenagers can still get the vaccine. And this was a very unusual move, since only 3 years ago, Japan’s parliament added the HPV vaccine to the mandatory schedule. Hopefully, this committee will look at the numbers from a statistical and scientific point of view and fix this stupidity.

By the way, the World Health Organization still recommends the HPV vaccine.  Because the HPV vaccine saves lives by preventing future cervical cancers.

 

Use the Science-based Vaccine Search Engine.

Key citations:

Vaccines saves lives–HPV scientific evidence part 2

 

© Copyright CSL, 2013. All Rights Reserved.
© Copyright CSL, 2013. All Rights Reserved.

Human papillomavirus (HPV) is a virus from the papillomavirus family that is capable of infecting humans. Like all papillomaviruses, HPVs establish productive infections only in keratinocytes of the skin or mucous membranes, making it easily transmitted sexually or through other intimate contact. While the majority of the known types of HPV cause no symptoms in most people, some types can cause warts (verrucae)HPV types 16 and 18 cause approximately 70% of cervical cancers, and cause most HPV-induced analvulvarvaginal, and penile cancers. The HPV quadrivalent vaccine, also known as Gardasil (or Silgard in Europe), is marketed by Merck. The vaccine prevents the transmission of certain types of HPV, specifically types 6, 11, 16 and 18

 

 

 

 

 

Continue reading “Vaccines saves lives–HPV scientific evidence part 2”

Religion vs Gardasil

gardasil.colorAlthough I rarely state it on these pages, I am an atheist. As a scientist, I’ve examined the evidence for a god (any god), and found it lacking. I think religion, especially in the USA, can be dangerous. Religious fundamentalism is behind the attack on teaching of real science, such as evolution and global warming. Although some may argue that trying to block the teaching of evolution, in favor of creationism, is innocuous (though absolutely unconstitutional), most would argue that since evolution is the basis of all biology (and therefore, medicine), it is harmful. 

It’s when fundamentalist religion gets involved in medicine, whether it’s therapeutic abortions, vaccines, or stem-cell research, that it’s clear that religion becomes dangerous to human lives. I just want to focus on one tiny corner of the medical world, where religious beliefs block good medicine–HPV vaccinations.

For those of you may be unfamiliar with the HPV vaccine, it prevents infection by the human papillomavirus (HPV), a sexually transmitted disease. The vaccine, known as Gardasil or Cervarix in the USA, specifically blocks HPV types 6, 11, 16 and 18; HPV types 16 and 18 cause approximately 70% of cervical cancers, and cause most HPV-induced analvulvarvaginal, and penile cancers. Cervical cancer, which afflicts 12,000 additional women and causes over 4,000 deaths annually in the USA, is considered the “preventable gynecologic cancer” because of the HPV vaccines. Continue reading “Religion vs Gardasil”

Survey identifies reasons for not vaccinating teens

vacs-save-lives-003Vaccines are one of the most important and crucial aspects for the long-term health of babies and young children. Except for a tiny, and irresponsible, minority of individuals who are opposed to vaccinations, greater than 95% of children are fully vaccinated for most vaccine preventable diseases by kindergarten. Unfortunately, a recently published article in Pediatrics provided evidence that teens are not keeping up with vaccinations that are critical to avoid infections from serious, and deadly, diseases. The study examines how vaccination rates have changed over the three year study period, and some of the reasons why they are not getting vaccinated. Continue reading “Survey identifies reasons for not vaccinating teens”

I get an email about Gardasil

hpv posterI get lots of email about my articles that are published here. Sometimes, it’s about grammar or spelling (and the grammar KGB can be uncivil at times). Sometimes, it’s compliments or questions about what I’ve written. Rarely, they’re rude and usually include quite immature comments about the location of my head. However, I recently received an email that is more or less polite, but is filled with so many errors and logical fallacies, that I thought it should be critiqued publicly.

Here are my point-by-point comments about the email:

I stumbled across your blog and could not believe what I was reading about the safety of Gardasil.  As a mother of a Gardasil injured daughter, your profuse endorsement made me skeptical.  I want to begin by saying I am not anti-vaccine;  I am anti-Gardasil.  Continue reading “I get an email about Gardasil”

HPV–early vaccination maximizes effectiveness

 

HPV protesters in Texas.

Human papillomavirus (HPV) is a virus from the papillomavirus family that is capable of infecting humans. Like all papillomaviruses, HPVs establish productive infections only in keratinocytes of the skin or mucous membranes, making it easily transmitted sexually or through other intimate contact. While the majority of the known types of HPV cause no symptoms in most people, some types can cause warts (verrucae). HPV types 16 and 18 cause approximately 70% of cervical cancers, and cause most HPV-induced anal, vulvar, vaginal, and penile cancers. The HPV quadrivalent vaccine, also known as Gardasil (or Silgard in Europe), is marketed by Merck. The vaccine prevents the transmission of certain types of HPV, specifically types 6, 11, 16 and 18

Although the safety of HPV vaccine has been thoroughly vetted for safety in studies with large cohorts, the long time period (up to decades) from infection to a diagnosis of an HPV-related cancer has left questions about how to maximize effectiveness of the vaccine which required further research.  Continue reading “HPV–early vaccination maximizes effectiveness”

Republican governor Nikki Haley is anti-vaccine and pro-cancer

The Charleston (SC) Post and Courier reports that Republican South Carolina Governor Nikki Haley vetoed a bill that would have provided sixth- and seventh-graders with information about the HPV vaccine. The vaccine would have been provided at no cost to all seventh-graders whose parents allowed them to have the vaccination. The bill had strong support from both Democrats and Republicans in the South Carolina legislature.

The HPV vaccine provides immunity to men and women against several types of human papilloma virus which is associated with with over 20,000 cancers in women and 11,000 cancers in men every year. Governor Haley defended her veto by calling the bill unnecessary and a “precursor to another taxpayer-funded healthcare mandate,” the Charleston Post and Courier reports.

State Rep. Bakari Sellers (D-Bamberg, S.C.) sponsored the bill and blasted Haley’s move, calling her decision one that… 

puts her own selfish political ambitions ahead of the people of South Carolina. This bill had bipartisan support and gives optional education and preventative vaccines to adolescents in an effort to thwart cervical cancer. This is a common sense approach to a very serious problem. To call this measure unnecessary is demeaning and insulting to the heroic women who fight this cancer everyday. I am deeply disappointed that politics once again has prevailed over women’s health.

In 2007, Haley actually co-sponsored a bill that would provide mandatory HPV vaccinations. It failed to pass through the legislature because it failed to provide opt-outs, which was corrected in the 2012 version.

Let’s be clear here. Haley did not veto this bill because of bad medicine or bad science. She vetoed it purely for political expediency and by doing so, she stands firmly against a simple inoculation that would prevent a deadly cancer. This is not a political issue, it is an anti-cancer issue. 

Vaccines save lives. I guess Nikki Haley doesn’t understand that! Maybe she’ll provide cigarettes for free to the school children of South Carolina.