Vaccine adverse events are very rare – vast benefits outweigh risks

shoenfeld

Like all medical procedures, devices, and pharmaceuticals, vaccines are not perfect – there are rare vaccine adverse events. What matters is that the benefits, not only medically but also economically, outweigh any risks. As far ask I know, no perfect medical procedures, devices, or pharmaceuticals, none, that are perfectly safe or perfectly effective. Sometimes the ratio is small.

For example, there are chemotherapy drugs that only add a few months to a patient’s life, usually with substantial side effects to the medication. Yet, if you ask a patient whether it was worth it, to spend just a few extra months with their children and loved ones, the value becomes nearly incalculable.

But mostly, the FDA and other regulatory agencies demand that new products and procedures must meet or exceed the safety, and meet or exceed the financial and health benefits of currently acceptable versions. Actually, the FDA examines a lot more than that.

They check the packaging, shelf life, instructions, manufacturing practices, and so much more, it would take a book to explain it (and there probably are several). It may not be a perfect process, but it’s better than what we had 100 years ago, and it continues to improve every single day. People tend towards a form of confirmation bias where they remember where a drug may have been found to be dangerous (the best example is Vioxx).

But they forget about the millions of medications and devices that save lives or measurably improve the standard of living. 

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Vaccine safety – a huge systematic review says they don’t cause autism

vaccine safety

Not that most of us need to be convinced, but there’s another huge systematic review that examined vaccine safety. Unsurprisingly, it shows that there are no major safety signals post-vaccination, plus no vaccine is linked to autism.

It’s ironic that this study is a high-quality systematic review and meta-analysis, the top of the hierarchy of biomedical research, while anti-vaxxers rely upon retracted articles published in predatory journals.

So, I want to do a quick review of this new article so that we can continue to support the settled science of vaccine safety.

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Autism and vaccines – 159 peer-reviewed scientific articles say no link

autism and vaccines

Autism and vaccines are not linked or associated according to real science, published in real scientific journals written by real scientists and physicians. But this false claim that vaccines and autism are related is repeated by anti-vaxxers nearly every day.

Let’s be clear – the lack of a link between vaccines and autism is settled science. There is overwhelming evidence, as listed in this article, that there is no link. Outside of anecdotes, internet memes, misinformation, and VAERS dumpster-diving, there is no evidence that there is a link. 

Ever since MrAndrew Wakefield published his fraudulent, and subsequently retracted, study that seemed to show a link between the MMR vaccine and autism spectrum disorder (ASD), the anti-vaccine crowd has embraced it as if it were a scientific fact. 

This Wakefield chicanery has spawned a cottage industry of other anti-vaccine zealots like Del Bigtree and his fraudumentary Vaxxed, Robert F. Kennedy Jr., Christopher Exley, Christopher Shaw, James Lyons-Weiler, Tetyana Obukhanych, and many others. 

This article presents 159 scientific articles, published in high-quality, peer-reviewed journals. Almost all of them are either primary studies that include large clinical trials or case-control or cohort studies. They also include numerous systematic reviews, which represent the pinnacle of biomedical research.

All of these articles, from some of the top vaccine scientists in the world, show that there are no links between autism and vaccines. None. 

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Vaccine profits from Big Pharma – let’s take a closer look at this trope

vaccine profits

The old myth of the huge Big Pharma vaccine profits – it’s the subject of so many memes, tropes, and outright lies from the anti-vaccine activists. These vaccine deniers, who not only lack knowledge of science but also of basic corporate finance, believe that every Big Pharma CEO relies on vaccines for their next bonus check, which they use to buy their new Ferrari to show off to imaginary vaccine-injured children.

I am not naive – public corporations have an obligation to their shareholders and employees to maximize profits. That’s capitalism, I suppose.

But where this trope goes off the rails is when you realize that vaccine profits would be eclipsed by medical industry profits if Big Pharma simply stopped producing vaccines – mass epidemics would mean that hospitals would be filled with patients, just look at the COVID-19 pandemic. It’s ironic that the anti-vaxxers claim that Big Pharma’s greed gives us vaccines, but if they were truly greedy they’d be out of the vaccine business.

This article is not going to be as much science as I usually do – it’s going to focus on finance and accounting. Yes, I’m a finance and accounting geek as much as I am a science aficionado. 

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National Vaccine Injury Compensation Program facts

national vaccine injury compensation program

This article about the National Vaccine Injury Compensation Program was written by Dorit Rubinstein Reiss, Professor of Law at the University of California Hastings College of the Law (San Francisco, CA), who is a frequent contributor to this and many other blogs, providing in-depth, and intellectually stimulating, articles about vaccines, medical issues, social policy, and the law.

Professor Reiss writes extensively in law journals about the social and legal policies of vaccination. Additionally, Reiss is also a member of the Parent Advisory Board of Voices for Vaccines, a parent-led organization that supports and advocates for on-time vaccination and the reduction of vaccine-preventable disease.

In this post I explain how one goes about proving a case in the  National Vaccine Injury Compensation Program (NVICP), and how that differs from proving a case in the civil courts, focusing on what it means to have a no-fault program and proving causation.

I will use a case that started with the tragic death of a young child after a vaccine to illustrate the complexity and operation of the program, and also to address the idea of federal preemption, and how it limits the ability of those claiming vaccine injuries to use state courts for their claims.

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MMR vaccine sytematic review – science finds no link to autism AGAIN

MMR vaccine systematic review

With so much sense and nonsense about coronavirus, I set to the side an important MMR vaccine systematic review that I’ve been wanting to review for a few weeks. Well, it’s time to focus on that.

Ever since MrAndrew Wakefield published his fraudulent, and subsequently retracted, study that seemed to show a link between the MMR vaccine and autism spectrum disorder (ASD), the anti-vaccine crowd has embraced it as if it were a scientific fact. Of course, they ignore over 150 published scientific articles that show that there are, in fact, no links at all.

This Wakefield chicanery has spawned a cottage industry of other anti-vaccine zealots like Del Bigtree and his fraudumentary Vaxxed, Robert F. Kennedy Jr., Christopher Exley, Christopher Shaw, James Lyons-Weiler, Tetyana Obukhanych, and many others. 

And now we have a new, large, impressive MMR vaccine systematic review that once again provides affirmative evidence that there are no links between ASD and the MMR vaccine. None. Continue reading “MMR vaccine sytematic review – science finds no link to autism AGAIN”

Vaccines and autism – robust, powerful science says they are unrelated

vaccines and autism

Vaccines and autism are not linked or associated according to real science, published in real scientific journals written by real scientists and physicians. But this false claim that vaccines and autism are related is repeated by anti-vaxxers nearly every day.

Let’s be clear – the lack of a link between vaccines and autism is settled science. There is overwhelming evidence, as listed in this article, that there is no link. Outside of anecdotes, internet memes, misinformation, and VAERS dumpster-diving, there is no evidence that there is a link. 

Probably as a result of reports that more and more children are being diagnosed with autism, people seem to be creating a false correlation (let alone causation) between vaccines and autism. So let’s take a look at the science.

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Andrew Wakefield is innocent – another vaccine denier trope and myth

andrew wakefield is innocent

The “Andrew Wakefield is innocent” trope that is rising again among the anti-vaxxer zombie claims being pushed recently. Professor Dorit Rubinstein Reiss critiques this claim in a 7-year-old article. I guess if the anti-vaccine loyalists can bring back old myths, we can bring back the solid refutation of them. This article also shows why Andrew Wakefield isn’t innocent whatsoever.

On March 7, 2012, Judge Mitting of the British High Court of Justice quashed the British General Medical Council (GMC)’s finding that Professor John Walker-Smith was guilty of serious professional misconduct. On November 21, 2014, for the umpteenth time, an anti-vaccine activist linked to the decision regarding Walker-Smith as evidence that Andrew Wakefield is innocent when the GMC found him, too, guilty of serious ethical violations.

The problem with this claim is that it is incorrect.

While others have examined the issue, it might be worth examining the decision closely yet again, since several tropes that Andrew Wakefield is innocent continue to come back to life.

Let’s start by examining the charges brought against Wakefield and Walker-Smith, using a side by side comparison of each charge. Continue reading “Andrew Wakefield is innocent – another vaccine denier trope and myth”

Atheists support vaccines – well, most Americans support MMR vaccine

atheists support vaccines

A new survey of Americans showed that they are overwhelmingly in favor of vaccines across all demographic groups. But atheists support vaccines more than any other religious designation.

Of course, this article isn’t really about how much atheists support vaccines, although that should be expected, given the fact that most atheists follow evidence rather than faith or beliefs. This article is going to review the detailed survey because if you’re anyone but Del Bigtree or Robert F Kennedy Jr, you’ll be fascinated to know that the vast majority of Americans support the MMR vaccine. Continue reading “Atheists support vaccines – well, most Americans support MMR vaccine”

Merck whistleblowers – mumps vaccine lawsuit motions and updates

merck whistleblowers

This article about the so-called Merck whistleblowers was written by Dorit Rubinstein Reiss, Professor of Law at the University of California Hastings College of the Law (San Francisco, CA), who is a frequent contributor to this and many other blogs, providing in-depth, and intellectually stimulating, articles about vaccines, medical issues, social policy, and the law.

Professor Reiss writes extensively in law journals about the social and legal policies of vaccination. Additionally, Reiss is also a member of the Parent Advisory Board of Voices for Vaccines, a parent-led organization that supports and advocates for on-time vaccination and the reduction of vaccine-preventable disease. She is also a member of the Vaccines Working Group on Ethics and Policy.

In August 2010 Stephen A. Krahling and Joan A. Wlochowski (“the relators”), former Merck virologists and often called “Merck whistleblowers,” filed suit in the name of the United States – a so-called qui tam action, where the prosecution shares any fines or penalties with the two virologists  – against Merck.

They claimed that by faking effectiveness testing, Merck misled the United States government as to the effectiveness of the mumps component of its  MMRII vaccine (a vaccine that protects individuals against mumps, measles, and rubella). In 2012  a clinic and two MDs filed a class action against Merck claiming a violation of the Sherman Act – monopolistic, anti-competitive behavior resulting from the fraud – and violation of various state laws. (U.S. v. Merck and Chatom v. Merck). The suits were handled together.

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