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MMR vaccine systematic review

MMR vaccine sytematic review – science finds no link to autism AGAIN

With so much sense and nonsense about coronavirus, I set to the side an important MMR vaccine systematic review that I’ve been wanting to review for a few weeks. Well, it’s time to focus on that.

Ever since MrAndrew Wakefield published his fraudulent, and subsequently retracted, study that seemed to show a link between the MMR vaccine and autism spectrum disorder (ASD), the anti-vaccine crowd has embraced it as if it were a scientific fact. Of course, they ignore over 150 published scientific articles that show that there are, in fact, no links at all.

This Wakefield chicanery has spawned a cottage industry of other anti-vaccine zealots like Del Bigtree and his fraudumentary Vaxxed, Robert F. Kennedy Jr., Christopher Exley, Christopher Shaw, James Lyons-Weiler, Tetyana Obukhanych, and many others. 

And now we have a new, large, impressive MMR vaccine systematic review that once again provides affirmative evidence that there are no links between ASD and the MMR vaccine. None. Read More »MMR vaccine sytematic review – science finds no link to autism AGAIN

merck whistleblowers

Merck whistleblowers – mumps vaccine lawsuit motions and updates

This article about the so-called Merck whistleblowers was written by Dorit Rubinstein Reiss, Professor of Law at the University of California Hastings College of the Law (San Francisco, CA), who is a frequent contributor to this and many other blogs, providing in-depth, and intellectually stimulating, articles about vaccines, medical issues, social policy, and the law.

Professor Reiss writes extensively in law journals about the social and legal policies of vaccination. Additionally, Reiss is also a member of the Parent Advisory Board of Voices for Vaccines, a parent-led organization that supports and advocates for on-time vaccination and the reduction of vaccine-preventable disease. She is also a member of the Vaccines Working Group on Ethics and Policy.

In August 2010 Stephen A. Krahling and Joan A. Wlochowski (“the relators”), former Merck virologists and often called “Merck whistleblowers,” filed suit in the name of the United States – a so-called qui tam action, where the prosecution shares any fines or penalties with the two virologists  – against Merck.

They claimed that by faking effectiveness testing, Merck misled the United States government as to the effectiveness of the mumps component of its  MMRII vaccine (a vaccine that protects individuals against mumps, measles, and rubella). In 2012  a clinic and two MDs filed a class action against Merck claiming a violation of the Sherman Act – monopolistic, anti-competitive behavior resulting from the fraud – and violation of various state laws. (U.S. v. Merck and Chatom v. Merck). The suits were handled together.

Read More »Merck whistleblowers – mumps vaccine lawsuit motions and updates
measles infections prevent heart disease

Measles infections prevent heart disease – an anti-vaccine trope

Here we go again, another anti-vaccine trope based on one paper without adequate scientific criticism of the said paper. What is this trope? Mumps and measles infections prevent heart disease and stroke. Let me jump right to the conclusion – wrong.

Although I’ve seen this story before, like most zombie tropes in the anti-vaccine world, this one has come back from the dead. In the pseudoscientific website, Health Impact Newsthe author writes:

By my calculations, natural infection with the measles and mumps will prevent millions of heart attacks and strokes. Why is this information not all over the TV and internet? I will tell you why. Because mainstream media is in bed with Big Pharma who pay their bills. The politicians are slaves to their corporate masters. Our children should be exposed to every virus and bacteria for which a vaccine exists.

The author’s shrill claim is based on a 2015 article published in the lower impact factor journalAtherosclerosis. The authors concluded that “measles and mumps, especially in case of both infections, were associated with lower risks of mortality from atherosclerotic CVD (cardiovascular disease).”

Now, it’s time to turn a critical and skeptical eye towards that article.Read More »Measles infections prevent heart disease – an anti-vaccine trope

measles epidemic

Measles epidemic in Europe is killing children – blame anti-vaccine religion

Maybe some of you haven’t been following the reports about the European measles epidemic, but it’s scary news. The BBC News reported that more than 41,000 people have contracted measles in the first six months of 2018. Worse yet, 37 of those people have died of that virus.

Let me be blunt – nearly every one of those 41,000 cases and 37 deaths could have been prevented by the MMR vaccine (for measles, mumps, and rubella). Period. Full stop. End of story.

In case I wasn’t clear, let me repeat myself – indulge me, we’re talking about children dying of an entirely preventable disease. Every single case of measles could have been prevented. Every single death could have been prevented. This isn’t a complicated story.

Maybe you think that Europe is a big area with over a half billion people, so this might be expected. That would be incorrect. Measles was almost extinct in much of the developed world. In 2016, there were just 5,273 measles cases for the whole year. In 2008, there were only 3,575 cases and one death. Measles was almost eliminated.

Let’s take a look at how this happened, and place blame right where it belongs – in the misinformation, pseudoscience, and outright lies of the anti-vaccine religionRead More »Measles epidemic in Europe is killing children – blame anti-vaccine religion

mumps vaccine

Mumps vaccine effectiveness – waning immunity may require 3rd dose

Over the past few years, there has been a resurgence in mumps outbreaks across the USA and other parts of the world. Although these outbreaks did not spread widely as they did before the advent of mumps vaccines, it still required some scientific research into why this happened. According to just published peer-reviewed research, much of the mumps outbreaks may result from waning mumps vaccine effectiveness.

Because I am concerned that this new article will be misinterpreted by some parts of the discussion, I’m glaring at the anti-vaccine religion, it is important that we take a very careful look at this well-done study examining what could be the root cause of some outbreaks – waning immunity to the mumps vaccine.Read More »Mumps vaccine effectiveness – waning immunity may require 3rd dose

Syracuse University mumps outbreak

Syracuse University mumps outbreak – bad anti-vaccine math

Partially because I’m an alumnus, and partially because I watch new reports about infectious disease outbreaks all over the world, I’ve been following the recent Syracuse University mumps outbreak. As of 13 November 2017, Syracuse University (SU) Health Services has reported 41 confirmed cases and 78 probable cases of the mumps on the SU campus.

One of the age-old tropes of the anti-vaccine statistics world is that kids who have been vaccinated against the mumps (or measles or any disease) are more likely to get mumps (or any disease) than those who are not vaccinated. I squashed this myth before, but you know what happens – the anti-vaccine zombie tropes tend to reappear over and over and over and over again.

Now, the anti-vaccine statistics deniers have jumped into the Syracuse University mumps outbreak with their alternative facts, or should I say alternative math. So, once more unto the breach, dear friends, once more. We will take down this trope.Read More »Syracuse University mumps outbreak – bad anti-vaccine math

vaccines prevented

Vaccines prevented 200 million cases of disease in the USA from 1963 to 2015

Lest we forget, vaccines are one of the greatest medical inventions of all time. Without them, we would see cemeteries filled with children who would have died before they were even five years old.  In fact, the best evidence we have tells us that vaccines prevented 200 million cases of diseases in the USA alone in the five decades since 1963.

A recent study, published in AIMS Public Health, estimates that around 200 million cases of polio, mumps, rubella, measles, adenovirus, hepatitis A and rabies have been prevented in the U.S. from 1963 through 2015 as a result of widespread vaccination. The study, authored by Leonard Hayflick and S. Jay Olshansky, two leading experts on public health and infectious diseases, also discloses that about 450,000 deaths have been avoided in the U.S during this period, although other studies put that estimate of lives saved at a much higher number.

Dr. Hayflick discovered the human cell strain, WI-38, in 1962 which was critical to the safe manufacturing of vaccines, which became widespread in 1963. According to the article, the vaccines produced from the WI-38 cell line prevented almost 4.5 billion occurrences of the diseases, and stopped them from returning to infect us. Dr. Hayflick developed the foundation that allowed the world to have relative safe and very effective tools to prevent infectious diseases.

Prior to the development of WI-38, anti-virus vaccines were grown in monkey cells, which had some issues that made many question their safety, although most of the concern appeared to be overblown. However, once the WI-38 was available, it became easier to develop and produce vaccines for many viruses.

Drs. Hayflick and Olshansky wanted to see what effect that seminal event had on public health. And the numbers were incredible.Read More »Vaccines prevented 200 million cases of disease in the USA from 1963 to 2015

mumps outbreaks

Mumps outbreaks in 2016 – highest number in over a decade

Over the past few years, there have been outbreaks of diseases we all assumed had been eradicated – chicken pox, measles, and, more recently, mumps. According to a report from the Centers for Disease Control and Prevention (CDC), there were over 4,000 mumps cases in the USA in 2016. Mumps outbreaks may be the new normal thanks to clusters of unvaccinated kids.

The mumps vaccination program started in 1967 – before that there were about 186,000 cases reported each year (and that number might be low because of underreporting). Once mumps vaccinations were commonplace, the incidence of the disease fell by over 99%. For those who think that better sanitation or whatever caused decreases in diseases, I think that 1967 is fairly recent, and it’s clear that the vaccine itself started the precipitous drop in mumps outbreaks. Since the start of the vaccine era, annual mumps cases in the USA hovered below 1,000 during most years. But over the last 10 years, there has been a noticeable uptick in annual cases, with a high of over 6,000 cases in 2006.

Let’s examine the mumps outbreaks and see what may be the cause. Spoiler alert – expect Andrew Wakefield’s name to appear.

Read More »Mumps outbreaks in 2016 – highest number in over a decade

Arizona measles outbreak

Arizona measles outbreak – blame anti-vaccine employees

Here we go again. Department of Health Services officials in Arizona  have reported that 22 confirmed measles cases in the state associated with a Federal immigration detention facility. This Arizona measles outbreak has one source – Federal employees of that facility who refused to get vaccinated against measles.

We all know why people don’t vaccinate their children with the MMR vaccine against measles, mumps and rubella – the zombie myth that vaccines cause autism, which has been so utterly debunked that it gives new meaning to the word, debunked.

Let’s take a look at the root of the Arizona measles outbreak. I’m sure there are lessons to be had there.

Read More »Arizona measles outbreak – blame anti-vaccine employees

Andrew Wakefield

Andrew Wakefield – dishonest attempt at self-justification

The movie Vaxxed is an anti-vaccine polemic that claims, despite all of the high quality contradictory evidence, that there is a link between the MMR vaccine, for mumps, measles and rubella, and autism. Furthermore, it claims that the US government is engaging in a conspiracy to hide said link. Reviews of the film have appropriately emphasized the checkered past of its director, Andrew Wakefield, a discredited ex-scientist with a history of misrepresentations. Many of the reviews point out that Wakefield is not a credible source for information on vaccines.

In a recent video posted on the Vaxxed website, Andrew Wakefield took those claims head on, mounting a passionate defense of his reputation. If anything, however, this video further shows that Wakefield is not a good source of information.

The video’s claims range from unsupported (and implausible) to blatantly false. Unfortunately for Wakefield, Brian Deer meticulously documented each step in the events, making it relatively easy to identify the problems in these claims. Unfortunately for the rest of us, Wakefield’s adherents are unlikely to check his claims, and others may also accept his word without fact-checking. It’s therefore worth going through the claims.

To hear Wakefield, he was the victim of a conspiracy mounted because he dared raise safety concerns about vaccines. But as with his book, Callous Disregard (pdf), Wakefield’s claims are ill founded. In short, there are good reasons he lost his license and his reputation as a serious scientist.

A brief review of the history of this story – in 1998, Wakefield and co-authors published a paper suggesting that the measles component of the measles-mumps-rubella (MMR) vaccine caused changes in some children’s guts, and that those changes were associated with autism.

In 2007, after extensive investigation by Brian Deer published at The Sunday Times, Britain’s General Medical Council (GMC) opened an investigation of their own to answer the question: Did Wakefield engage in serious professional misconduct?  In May 2010, the GMC found that yes, he did, and removed Wakefield from the British medical register (pdf).

Wakefield’s claims in the Allegations video can be put into three categories:

  1. there were no serious ethical violations or fraud in relation to the article he published in the Lancet;
  2. he’d done nothing wrong otherwise, measles outbreaks are not his fault, the GMC decision was generally wrong, and Walker-Smith’s acquittal shows that; and
  3. Brian Deer’s articles are a fraud motivated by a conspiracy.

None of these claims hold water.

Read More »Andrew Wakefield – dishonest attempt at self-justification