Peter Doshi and FDA approval of Pfizer COVID vaccine – what now?

Doshi Pfizer COVID vaccine

Once again, the anti-vaccine shill, Peter Doshi, uses his BMJ blog to complain about the recent Pfizer/BioNTech COVID-19 vaccine approval by the US FDA. I’ve already seen anti-vaccine activists use this as a “peer-reviewed paper that shows that the vaccine is dangerous.” First, it is not peer-reviewed, it is a blog post no different than the one I’m writing right now. Second, it’s an opinion piece, he’s not showing any original or even secondary research to support his wild claims.

BMJ is not a hotbed of anti-vaccine pseudoscience, except for the presence of Peter Doshi. For example, they published a series of articles, written by Brian Deer, about Andrew Wakefield’s despicable deceit, you can read about it herehere, and here. Deer has also written a powerful book about Wakefield’s fraud. I wonder what Mr. Deer thinks of Peter Doshi as an editor at the acclaimed medical journal.

Even though anyone with the least bit of scientific expertise understands that whatever Peter Doshi says about the Pfizer COVID-19 vaccine FDA approval is nonsense, I will endeavor to take apart his ridiculous claims.

Continue reading “Peter Doshi and FDA approval of Pfizer COVID vaccine – what now?”

FDA approval of Pfizer COVID vaccine – why did it take so long?

FDA approval pfizer COVID-19 vaccine

One of the questions I keep seeing is why did it take so long for FDA approval of the Pfizer/BioNTech COVID-19 vaccine, Comirnaty? The answer is complicated, but the basic issue is that the FDA is very conservative in approving drugs – I bet that will surprise everyone.

I’m going to delve into a couple of issues with the FDA and its approval of the Pfizer COVID-19 vaccine. Even though some people argue that it took too long to go from the Emergency Use Authorization (EUA) to full approval, it was, in fact, fairly rapid. Remember, clinical trials only commenced maybe 15 months ago, so this is warp speed compared to the usual vaccine timeline that may be nearly 10 years.

Many of us thought that it would take up to three years before we had COVID-19 vaccines available – I’m willing to eat humble pie on blowing that prediction, but it’s amazing what happens when governments, scientists, and pharmaceutical companies can do when they are all focused on a common goal. Not for nothing, but why can’t we do the same thing with climate change – a lot more of us are at risk of that than COVID-19, but I’ll leave that for another day.

Let’s take a brief look at why some of you are wondering why it took so long for the FDA approval of the Pfizer COVID-19 vaccine.

Continue reading “FDA approval of Pfizer COVID vaccine – why did it take so long?”

Peter Doshi discusses COVID vaccine clinical trials – once again, he’s wrong

anti-vaccine peter doshi

One of the most annoying anti-vaccine activists is Peter Doshi who has decided to pontificate on COVID-19 vaccine trials. He is bothersome not because he is a noteworthy scientist or physician, he’s not, it’s because he somehow scored a position as an editor at the respected medical journal, BMJ (formerly known as the British Medical Journal).

BMJ is not a hotbed of anti-vaccine pseudoscience, except for the presence of Peter Doshi. For example, they published a series of articles, written by Brian Deer, about Andrew Wakefield’s despicable deceit, you can read about it herehere, and here. Deer has also written a powerful book about Wakefield’s fraud. I wonder what Mr. Deer thinks of Peter Doshi as an editor at the acclaimed medical journal.

Doshi occasionally uses BMJ as his personal bully pulpit to push anti-vaccine rhetoric that can lead the casual observer to think that he is some respected authority figure with vaccines. He isn’t.

Peter Doshi has just posted an anti-vaccine blog post on BMJ attacking the clinical trials for the Pfizer and Moderna COVID-19 vaccines.  His opinion piece needs to be critiqued because his attacks can add to the vast number of anti-COVID-19 vaccine myths that are being spread across the internet. 

Continue reading “Peter Doshi discusses COVID vaccine clinical trials – once again, he’s wrong”

H1N1 flu vaccine – Peter Doshi invents a myth about GSK Pandemrix

H1N1 flu vaccine

During the 2009-10 flu season, public health officials across the world were concerned about a flu pandemic caused by the H1N1 influenza virus. In response to the dangerous new flu, these same public health officials made certain to protect their citizens with new a new H1N1 flu vaccine that would protect individuals from the pandemic H1N1 flu virus.

There have been two H1N1 flu pandemics in recent history. The first, the 1918 pandemic, also called the Spanish Flu, infected over 500 million people worldwide (when the planet only had about 2.5 billion humans) and killed between 50-100 million. And no, it didn’t target babies and the elderly, it killed everyone targeting healthy young adults.

In the USA alone, the US Centers for Disease Control and Prevention estimated that the 2009 pandemic resulted in over 43-89 million cases, 195-403 thousand hospitalizations and between 8,870 and 18,300 deaths. The CDC also estimated that over 300,000 people died worldwide from the 2009 H1N1 flu.

No wonder the world’s public health authorities made sure the H1N1 flu vaccine was widely available. I cannot imagine what those numbers would have been without it – possibly millions of deaths worldwide.

Recently, anti-vaccine hawker, Peter Doshi, continues with his perverse, pseudoscientific assaults on flu vaccines by now using a ridiculously amateurish conspiracy to invent safety concerns about the 2009 H1N1 flu vaccine. I’m not one to let this nonsense pass, so here goes. Continue reading “H1N1 flu vaccine – Peter Doshi invents a myth about GSK Pandemrix”

Peter Doshi, anti-vaccine false authority, back again to push fake science

Peter Doshi

The bloviating Peter Doshi, who loves all things anti-vaccine, filed a lawsuit against Health Canada, essentially, the Ministry of Health for the country and the ministry that regulates medications and vaccines for Canada, to retrieve all of the clinical trial data for HPV vaccines that was used to get approval for the vaccines in the country (see Note 1). He recently won that lawsuit, and, unless Health Canada appeals the ruling, so we can assume he will receive mountains of data to “analyze.”

According to an article in the CBC, the ruling gives Doshi access to clinical trial data submitted to Health Canada by the manufacturers of HPV vaccines, Gardasil, Gardasil9, and Cervarix, and of anti-viral flu medications. Doshi wants to do a “systematic review” of the findings, although I don’t think that’s what a systematic review is, we’ll discuss that below. Health Canada argued that the data was confidential, and they would only hand over the data if he signed a non-disclosure agreement. Doshi refused, and he prevailed in the lawsuit.

You may have read all of this and wondered who is this Peter Doshi and why do I dislike him so. Well, most of you know of Doshi. And then you wonder why I care at all that he gets this data. I actually don’t care, but I should talk about it anyway.

So, let’s talk about the false authority, Peter Doshi, and why it matters or not that he gets this data. Spoiler alert – it doesn’t matter, but we should be prepared. Continue reading “Peter Doshi, anti-vaccine false authority, back again to push fake science”

Once more about Andrew Wakefield fraud extraordinaire

For the handful of you who don’t know him, MrAndrew Wakefield fraudulently alleged a connection between the MMR vaccine, for measles, mumps and rubella) and autism – this has had the effect of suppressing vaccination rates in many countries. His claims were published in a now retracted paper published in the Lancet, a mostly respected medical journal who seemed to have forgotten how to do proper peer review back in the late 1990’s. This is a quick review of the Andrew Wakefield fraud.

Dorit Rubinstein Reiss – Professor of Law at the University of California Hastings College of the Law (San Francisco, CA) – is a frequent contributor to this blog. She had posted an article that debunks the myth that Andrew Wakefield is probably innocent of all charges made against him by the UK’s General Medical Council (GMC). Basically, some of the antivaccination crowd believes that because Wakefield’s partner in the fraud, Professor John Walker-Smith, had his own decision by the GMC overturned, it is considered evidence that Andrew Wakefield was wronged when the GMC found Wakefield, too, guilty of serious ethical violations. But that would be an incorrect interpretation of the facts. Continue reading “Once more about Andrew Wakefield fraud extraordinaire”

Peter Doshi flu vaccine study – misused by anti-vaxxers

Peter Doshi

Anti-vaccine activists constantly look for any science that seems to support their beliefs about the safety and effectiveness of vaccines. Lately, they have gravitated to the writings of Peter Doshi, who has made a career talking about vaccines. Although Doshi lacks the credentials in any area of science related to vaccines – immunology, microbiology, virology, public health, epidemiology – the anti-vaccine forces embrace him like he’s a Nobel Prize winning scientist. Which he is not.

Let’s take a look at Doshi’s credentials and what he’s written about vaccines, specifically the flu vaccine. Continue reading “Peter Doshi flu vaccine study – misused by anti-vaxxers”

Peter Doshi, vaccine denier, sees a conspiracy about VAERS

Peter Doshi

I am not a fan of Peter Doshi, one of the go-to “authorities” for the anti-vaccine crowd. He has no credentials that would indicate that he is an expert in vaccines, yet one of his opinion pieces (not real science lacking data and evidence) is used as “proof” that flu vaccines don’t work. And of course, like all zombie memes of the anti-vaccine universe, it comes around every year or so, requiring a new debunking.

So what is he going on about now? The Poxes Blog reports that Doshi seems to think that something foul and evil is going on with the VAERS database. Sigh.

Let’s talk about Peter Doshi and his latest conspiracy theory. It’s always fun.

 

Continue reading “Peter Doshi, vaccine denier, sees a conspiracy about VAERS”

The annual report of Skeptical Raptor’s blog–2014

2014-annual-report

Actually, it’s not so annual, cause this is the first time I’ve done it, more or less.

I started this blog in January 2012. Just three years ago. I really didn’t know what subjects would be my focus, but it was science generally. I kind of wandered around for the first few months, before I think I hit my stride with vaccines, junk medicine, evolution (though I really need to move back into that area), and other things that captured my interest.

In January 2012, I had precisely 262 page views. For the whole month. I really thought “why bother.” For 2012, I had 184,000 page views, which still made me wonder if the effort was worth it.

In November 2014, I had over 278,000 unique page views, meaning I did more in November than I did in all of 2012. For 2014, I had nearly 1.2 million unique page views, which meant this website is ranked 278,000th in the world. OK, that sounds terrible, except that there’s 1,200,000,000 (1.2 billion if you hate counting zeroes) websites on the interwebs as of this moment. So this blog ranks in the top 0.023% of all websites on the internet. It’s no Facebook or Amazon, but then again, I have reach goals for this blog, and those aren’t it!

My goal is to provide scientific evidence for science and medicine, while doing the same against pseudoscientific myths and memes that are popular on the social networks. I do it with my style–take no prisoners, and use the highest standards of evidence. I refuse to accept a cherry-picked study that supports an a priori conclusion, when the scientific consensus, based on a mountainous body of evidence, is a formidable fortress of knowledge.

I seriously get frustrated when people think that their opinion somehow trumps the scientific consensus. Or that they think they can lie or intentionally abuse data to fit their “beliefs.” Climate change deniers. Evolution deniers. Vaccine deniers. GMO deniers. HIV/AIDS deniers. All use the same methodology to make their points. Whining about so-called problems, based on nonsense and ignorance. Depending upon false authorities to “prove” that the denier point of view deserves respect. Finding the one study that is an outlier, and ignoring the mountains of evidence supporting the scientific consensus. Providing false-balanced presentations that make it appear that there is really a debate. Using personal attacks and conspiracy theories to attack the character of thoughtful and intellectually superior science supporters.

If it weren’t so dangerous, we’d laugh at these people. Well, I still mock them, but I know they are dangerous lunatics.

Continue reading “The annual report of Skeptical Raptor’s blog–2014”

Did you get your flu vaccination?–2014 version

flu-shot-calendarThere is substantial scientific evidence that the flu immunization is both very safe and very effective. Unless you follow the ramblings of a non-immunologist, non-virologist, non-epidemiologist, non-scientist, Peter Doshi who has published outright fabrications about the safety and effectiveness of the flu vaccine, you probably fall on the side of getting vaccinated. Maybe.

But some people refuse the flu vaccine because of adherence to easily debunked myths and misinformation. If you are on the fence about the flu vaccine, read Tara Haelle’s It’s Baaaaack! 33 Flu Vaccine Myths You Don’t Need to Fear. She worked hard to put that list together, so if you’re on the fence about the flu vaccine, read it before the flu season takes off. You won’t be sorry.

Or you can be a real dumbass and accept the lamest excuses for not getting the flu vaccine.

OK, what is your flu vaccination status? And if you have any comments, just drop them into the Disqus comments below. We’d especially like to hear from people on the fence, maybe we can give you some gentle persuasion to get the vaccine!