Flawed Lyons-Weiler vaccine study further critiqued by a real scientist
This review primarily stemmed from my previous blog post in which I pointed crucial experimental flaws in the most recent study published by Lyons-Weiler and colleagues [1]. The reply was swift and expected, a diatribe written on his own page that was vociferous, slanderous and completely inappropriate for a public statement.
I was surprised that a man claiming to be from science, and that should be “seasoned” by now about handling on critiques from reviewers would have shown an unmeasured tone in such official communication.
Surprised? I was not, and confirmed the reason why I use a pen name. Before submitting it as a post, I considered directly sending my letter to the editor of the journal, only to recuse from it by fear of retaliation and harassment from Lyons-Weiler or by some random anti-vaccine person to my institution.
In this delicate period of my academic career, such a decision can have devastating consequences on unfolding events related to my career. Shall I be in a better position, I would not have hesitated to send the letter to the editor.
Interestingly, such a slanderous attack of the messenger seems a staple amongst anti-vaccine crowds, but not expected from scientists. Yet, such slanderous behavior is not exclusive to the author. Recently, a letter to editor written by peers of the authors (in the name of Christopher Exley, Christopher Shaw, and Romain Gherardi as they co-authored the retracted counter-letter) was judged so slanderous against a scientist that raised important and valid concerns on a study published by Crepeaux and colleagues in “Toxicology” journal [2].
It is important to note to the reader not familiar with academic publishing that the retraction of a letter to the editor is so rare, that it suggests the extreme gravity of the slanderous claims made.
More recently, a similar behavior (albeit less slanderous) came from the recent retraction of the recent study by DeLong and colleagues [3], following critiques and concerns on PubPeer. Instead of addressing directly the stipulations raised by readers, the author underwent a series of diatribes while failing to address the major flaws of the paper.
During my professional development, learning to accept rejection and criticism from peer-reviews (be it a manuscript submitted to a journal or a grant proposal) is part of being a scientist. We do not mince words, and we will say bluntly (but with academic finesse) when a study or grant is not considered “competitive” and “compelling”.
We learn to undergo the stage of grievance and learn to deal with it several times a year. Yet, we also learn to never ever write a reply in the spur of the moment, in the full rage and anger. One day, my department chair told us (in one of these lab meetings) to never ever send an angry letter because you may regret (and will likely regret) it later.
Sending an angry letter will not change the editor or program officer to accept your paper or your grant proposal. Worse, it will backfire on you and reduce your chance of having your manuscript or grant proposal accepted in the future, as you will be labeled “that annoying scientist”.
Sure, write that angry letter. But don’t send it. Leave it to sediment overnight on your desk and come back to it the day after and re-read it. You will be surprised once the haze of anger is gone how callous and slanderous the letter was and failed to make a constructive and detailed counter-response to the reviewers.
This post is not intended to be a counter-response to Lyons-Weiler, that would be futile and sterile. However, I want to use this as a learning experience by using a study cited by the author [4] that Lyons-Weiler used against me as it claims it vindicates him (*spoilers* it does not, quite the opposite indeed. Read the rest of the post to have a detailed explanation) and discuss on why this study is indeed adding an additional stone in making the point of the overall safety of aluminum adjuvants in vaccines.
For those coming from his page, I want you to come with a neutral and objective mind and read carefully the following sections and follow me through my review. To the authors of this study, I would like to address you my fullest gratitude for your recent work published by your research group in helping advance the (very) complicated and punctuated literature on the pharmacokinetics of aluminum adjuvants over the last 40 years.
My apologies if I use your figures in this post, but I consider it essential to provide these to the readers that may not have access to your publication.Read More »Flawed Lyons-Weiler vaccine study further critiqued by a real scientist