Calorie restricted diets and the effect on aging

There has been a belief that has been promoted over the years that very low calorie diets can promote lifespan. It was based on a 1934 research study from Mary Crowell and Clive McCay, at Cornell University, who observed that laboratory rats fed a severely reduced calorie diet, while maintaining micronutrient levels, would result in lifespans of up to twice as long as control groups. Their findings were later repeated by Roy Walford, and his student Richard Weindruch, through a series of experiments with mice. In 1986, Weindruch reported that restricting the caloric intake of laboratory mice proportionally increased their life span compared to a group of mice with a normal diet. The calorie-restricted mice also maintained youthful appearances and activity levels longer and showed delays in age-related diseases. The results of the many experiments by Walford and Weindruch were summarized in their book, The Retardation of Aging and Disease by Dietary Restriction. Continue reading “Calorie restricted diets and the effect on aging”