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MMR vaccine systematic review

MMR vaccine sytematic review – science finds no link to autism AGAIN

With so much sense and nonsense about coronavirus, I set to the side an important MMR vaccine systematic review that I’ve been wanting to review for a few weeks. Well, it’s time to focus on that.

Ever since MrAndrew Wakefield published his fraudulent, and subsequently retracted, study that seemed to show a link between the MMR vaccine and autism spectrum disorder (ASD), the anti-vaccine crowd has embraced it as if it were a scientific fact. Of course, they ignore over 150 published scientific articles that show that there are, in fact, no links at all.

This Wakefield chicanery has spawned a cottage industry of other anti-vaccine zealots like Del Bigtree and his fraudumentary Vaxxed, Robert F. Kennedy Jr., Christopher Exley, Christopher Shaw, James Lyons-Weiler, Tetyana Obukhanych, and many others. 

And now we have a new, large, impressive MMR vaccine systematic review that once again provides affirmative evidence that there are no links between ASD and the MMR vaccine. None. Read More »MMR vaccine sytematic review – science finds no link to autism AGAIN

measles epidemic

Measles epidemic in Europe is killing children – blame anti-vaccine religion

Maybe some of you haven’t been following the reports about the European measles epidemic, but it’s scary news. The BBC News reported that more than 41,000 people have contracted measles in the first six months of 2018. Worse yet, 37 of those people have died of that virus.

Let me be blunt – nearly every one of those 41,000 cases and 37 deaths could have been prevented by the MMR vaccine (for measles, mumps, and rubella). Period. Full stop. End of story.

In case I wasn’t clear, let me repeat myself – indulge me, we’re talking about children dying of an entirely preventable disease. Every single case of measles could have been prevented. Every single death could have been prevented. This isn’t a complicated story.

Maybe you think that Europe is a big area with over a half billion people, so this might be expected. That would be incorrect. Measles was almost extinct in much of the developed world. In 2016, there were just 5,273 measles cases for the whole year. In 2008, there were only 3,575 cases and one death. Measles was almost eliminated.

Let’s take a look at how this happened, and place blame right where it belongs – in the misinformation, pseudoscience, and outright lies of the anti-vaccine religionRead More »Measles epidemic in Europe is killing children – blame anti-vaccine religion

vaccines prevented

Vaccines prevented 200 million cases of disease in the USA from 1963 to 2015

Lest we forget, vaccines are one of the greatest medical inventions of all time. Without them, we would see cemeteries filled with children who would have died before they were even five years old.  In fact, the best evidence we have tells us that vaccines prevented 200 million cases of diseases in the USA alone in the five decades since 1963.

A recent study, published in AIMS Public Health, estimates that around 200 million cases of polio, mumps, rubella, measles, adenovirus, hepatitis A and rabies have been prevented in the U.S. from 1963 through 2015 as a result of widespread vaccination. The study, authored by Leonard Hayflick and S. Jay Olshansky, two leading experts on public health and infectious diseases, also discloses that about 450,000 deaths have been avoided in the U.S during this period, although other studies put that estimate of lives saved at a much higher number.

Dr. Hayflick discovered the human cell strain, WI-38, in 1962 which was critical to the safe manufacturing of vaccines, which became widespread in 1963. According to the article, the vaccines produced from the WI-38 cell line prevented almost 4.5 billion occurrences of the diseases, and stopped them from returning to infect us. Dr. Hayflick developed the foundation that allowed the world to have relative safe and very effective tools to prevent infectious diseases.

Prior to the development of WI-38, anti-virus vaccines were grown in monkey cells, which had some issues that made many question their safety, although most of the concern appeared to be overblown. However, once the WI-38 was available, it became easier to develop and produce vaccines for many viruses.

Drs. Hayflick and Olshansky wanted to see what effect that seminal event had on public health. And the numbers were incredible.Read More »Vaccines prevented 200 million cases of disease in the USA from 1963 to 2015

Arizona measles outbreak

Arizona measles outbreak – blame anti-vaccine employees

Here we go again. Department of Health Services officials in Arizona  have reported that 22 confirmed measles cases in the state associated with a Federal immigration detention facility. This Arizona measles outbreak has one source – Federal employees of that facility who refused to get vaccinated against measles.

We all know why people don’t vaccinate their children with the MMR vaccine against measles, mumps and rubella – the zombie myth that vaccines cause autism, which has been so utterly debunked that it gives new meaning to the word, debunked.

Let’s take a look at the root of the Arizona measles outbreak. I’m sure there are lessons to be had there.

Read More »Arizona measles outbreak – blame anti-vaccine employees

Andrew Wakefield

Andrew Wakefield – dishonest attempt at self-justification

The movie Vaxxed is an anti-vaccine polemic that claims, despite all of the high quality contradictory evidence, that there is a link between the MMR vaccine, for mumps, measles and rubella, and autism. Furthermore, it claims that the US government is engaging in a conspiracy to hide said link. Reviews of the film have appropriately emphasized the checkered past of its director, Andrew Wakefield, a discredited ex-scientist with a history of misrepresentations. Many of the reviews point out that Wakefield is not a credible source for information on vaccines.

In a recent video posted on the Vaxxed website, Andrew Wakefield took those claims head on, mounting a passionate defense of his reputation. If anything, however, this video further shows that Wakefield is not a good source of information.

The video’s claims range from unsupported (and implausible) to blatantly false. Unfortunately for Wakefield, Brian Deer meticulously documented each step in the events, making it relatively easy to identify the problems in these claims. Unfortunately for the rest of us, Wakefield’s adherents are unlikely to check his claims, and others may also accept his word without fact-checking. It’s therefore worth going through the claims.

To hear Wakefield, he was the victim of a conspiracy mounted because he dared raise safety concerns about vaccines. But as with his book, Callous Disregard (pdf), Wakefield’s claims are ill founded. In short, there are good reasons he lost his license and his reputation as a serious scientist.

A brief review of the history of this story – in 1998, Wakefield and co-authors published a paper suggesting that the measles component of the measles-mumps-rubella (MMR) vaccine caused changes in some children’s guts, and that those changes were associated with autism.

In 2007, after extensive investigation by Brian Deer published at The Sunday Times, Britain’s General Medical Council (GMC) opened an investigation of their own to answer the question: Did Wakefield engage in serious professional misconduct?  In May 2010, the GMC found that yes, he did, and removed Wakefield from the British medical register (pdf).

Wakefield’s claims in the Allegations video can be put into three categories:

  1. there were no serious ethical violations or fraud in relation to the article he published in the Lancet;
  2. he’d done nothing wrong otherwise, measles outbreaks are not his fault, the GMC decision was generally wrong, and Walker-Smith’s acquittal shows that; and
  3. Brian Deer’s articles are a fraud motivated by a conspiracy.

None of these claims hold water.

Read More »Andrew Wakefield – dishonest attempt at self-justification

2013-14 vaccine uptake in the USA is still high

voices-for-vaccinesDespite the continued social network misinformation about vaccine safety and/or effectiveness, the United States Centers for Disease Control and Prevention (CDC) has reported that the median vaccination coverage, amongst children between the age of 19-35 months was 94.7% for 2 doses of measles, mumps, and rubella (MMR) vaccine; 95.0% for varying local requirements for diphtheria, tetanus toxoid, and acellular pertussis (DTaP) vaccine; and 93.3% for 2 doses of varicella vaccine among those states with a 2-dose requirement.

The median total exemption rate was 1.8%, a difficult number to truly analyze. The CDC reported many issues like some parents get an exemption even after their children are fully or partially vaccinated, some exemptions are used as a matter of convenience because the parents forgot to vaccinated, and some states don’t report exemptions. Moreover, the CDC data indicates up to 15% of exemptions are “medical,” meaning that a child cannot receive a vaccine as a result of an establish medical contraindication.

Although these numbers fall near the 95% vaccination rate goal establish by the CDC’s Health People 2020there is still a concern that clusters of unvaccinated or under-vaccinated children exist in many states and areas. Those locations become susceptible to outbreaks of vaccine-preventable diseases. Moreover, 26 states and DC failed to meet the 95% goal, so the disparity between vaccinated and unvaccinated groups remain large.

The research also shows that there have been no statistically significant changes in either vaccination or exemption rate from 2012-13. This is more statistical support that the antivaccination agenda is not gaining much traction across most of the USA.

Read More »2013-14 vaccine uptake in the USA is still high

Hey vaccine deniers–it’s just simple math. Part deux.

This article has been updated, and you can read it here. The comments section to this article have been closed, but you can comment at the newer version.

 

A few days ago, I wrote an article discussing how antivaccination trope inventors could not understand the most basic elements of mathematics in reading a vaccine label. They misinterpreted some simple math like that the toxic level of a substance is several million times higher than what is injected. I suppose in the minds of vaccine deniers, 1=1 billion. Or 1 trillion. Or 4783.2226. It just depends.

And if they can’t understand the simplest of math principles, assuming that they would understand population level statistics might be a really bad assumption.

Recently, I was pointed to an antivaccination article, on the Political Blindspot website, which is dedicated to finding news articles swept under the rug by mainstream media. My skeptical radar always goes into full energy mode whenever I see the word “mainstream.”Read More »Hey vaccine deniers–it’s just simple math. Part deux.

Measles, mumps, rubella outbreaks–the culpability of Andrew Wakefield

Wakefield-fraudThis week, writer Aaron Carroll provided a graphic depiction of the toll of the antivaccination movement, which itself comes from a Council on Foreign Relations interactive map of “vaccine-preventable outbreaks” worldwide 2008-2014. I narrowed down the map to just include measles, mumps, and rubella, three diseases that can and are prevented by the MMR (or more commonly in the USA, MMRV, which includes chickenpox) vaccine.

Even though the vaccine deniers champion the trope that these diseases are “not serious,” real evidence from real infectious disease medical specialists say otherwise. Measles, mumps and rubella can be dangerous diseases with debilitating complications, including death, for both children and adults. And as you can see in the map (click on it for greater detail), outbreaks of measles (in red), mumps (in olive) and rubella (in blue) are larger than it should be in both the developed and the developing world than it should be, given the easy access to the MMR (or MMRV) vaccines.Read More »Measles, mumps, rubella outbreaks–the culpability of Andrew Wakefield

Why we vaccinate–103 million cases of diseases averted since 1924

vaccines-vs-microbes

For New Year’s Day, I’m republishing the top 10 articles I wrote in 2013. Well, actually top 9, plus 1 from 2012 that just keeps going.

#10. This article was published on 3 December 2013, and has had over 5000 views. It’s one of my favorite because it shows, with scientific evidence, that the trope pushed by the vaccine deniers that better sanitation, food, and medicine reduced the mortality from these diseases. But we know it’s the vaccines, and we have brilliant science to support that fact.

One of the tropes of the antivaccination world is that vaccines didn’t stop diseases. They give credit to everything from modern medicine to better food to better sanitation. Some of the credit they give is ironic since many vaccine deniers hate most aspects of modern medicine and believe that food was better 100 years ago. You can never get enough of the contradictions and hypocrisy of the antivaccine crowd.

I think it becomes easy to dismiss the value of vaccines in ending widespread disease because almost anyone writing today about vaccines has no memory of ubiquitous and deadly epidemics of diseases. We’re almost at a point in our culture that if Twitter doesn’t report it, it didn’t happen, so infectious diseases are something that happened back when humans lived in caves, prior to the advent of social media. I happen to have been born right near the end of widespread epidemics of infectious diseases, so I don’t remember any epidemics personally, though I recall a few classmates in high school who had a few effects from polio and other diseases. Culturally, we have forgotten our past with respect to diseases.Read More »Why we vaccinate–103 million cases of diseases averted since 1924

Delaying measles vaccination may increase risk of seizures

keep-calm-get-shots-bigThere is an unscientific myth, pushed by some parts of the vaccine deniers (more accurate, vaccine delayers), that parents should delay vaccinations based on the unsupported belief that “too many vaccines” could overwhelm the child’s immune system. This belief is utterly unscientific and thoroughly debunked

That belief is unfounded, as Paul Offit summarized in Addressing Parents’ Concerns: Do Multiple Vaccines Overwhelm or Weaken the Infant’s Immune System?:

Current studies do not support the hypothesis that multiple vaccines overwhelm, weaken, or “use up” the immune system. On the contrary, young infants have an enormous capacity to respond to multiple vaccines, as well as to the many other challenges present in the environment. By providing protection against a number of bacterial and viral pathogens, vaccines prevent the “weakening” of the immune system and consequent secondary bacterial infections occasionally caused by natural infection.

Read More »Delaying measles vaccination may increase risk of seizures