Vaccine challenge studies – can it speed up coronavirus vaccine licensing?

Yesterday, I discussed the difficulty of developing a new coronavirus vaccine. However, vaccine challenge studies may be one way to speed up the timeline for us to get a vaccine for COVID-19.

But, and there’s always a but, vaccine challenge studies test the limits of biomedical ethics and quality of results. 

Because it is important to review all aspects of coronavirus vaccine development, I wanted to spend a few moments of your time discussing this method of clinical testing of a new vaccine. Continue reading “Vaccine challenge studies – can it speed up coronavirus vaccine licensing?”

Coronavirus vaccine development – it’s going to take a long time

Coronavirus vaccine development

I keep reading this belief, over and over, that by some miracle, coronavirus vaccine development will only take “12-18 months.” Like a lot of things in life, we keep repeating that mantra, but when anyone tries to find any veracity in that claim, there’s little there.

I know this is like the hundredth article I’ve posted on coronavirus vaccines. I just joked with someone that if I wrote an article that conclusively established that aluminum adjuvants in vaccines actually cured cancer, erectile dysfunction, and the inability to hit an inside curveball, the first 30 comments posted at the end of that article would ask, “yeah that’s nice to know, old dinosaur. But does it cure COVID-19?”

But the common theme I keep hearing is that coronavirus vaccine development will go super fast, and we’ll have that vaccine in 12-18 months. Then we can go back to fun times like watching that inside curveball at a baseball game, scaring away wildlife at our National Parks, and sitting in our friendly diner consuming thousands of calories. 

Even Dr. Anthony Facui, whose facial expressions in response to whatever lie that Donald Trump is saying during his daily coronavirus campaign events are meme-worthy, has said that we might see a vaccine within 12-18 months. Now, Dr. Fauci is a billion times smarter than this old raptor, but I am very skeptical. 

Maybe he has some inside knowledge. Maybe he has seen some secret data only available only to him and Bill Gates. Maybe Trump has a gun pointed at him during these campaign rallies. Or maybe he just believes it because he’s an optimistic person, and he doesn’t want people to give up knowing that it could take three or more years for a vaccine.

I don’t know the real answer, but a lot of vaccine experts who have spent their lifetime studying vaccines, and they are very skeptical of this aggressive coronavirus vaccine development timeline. 

I know I’ve been repeating myself over and over and over about coronavirus vaccine development, but I just think that we’re doing a disservice to public health by placing bets on a COVID-19 vaccine being out there any time within that timeframe. Continue reading “Coronavirus vaccine development – it’s going to take a long time”

Chloroquine for coronavirus, I mean the Trumpvirus – evidence is weak

chloroquine for coronavirus

I’m sure you’ve all heard that President Trump has pushed chloroquine for coronavirus treatment. He claims that there is good evidence supporting it, but if we actually look at that evidence, is there anything there?

Once again, here’s a spoiler alert – the evidence supporting chloroquine for coronavirus is extremely weak. And there seem to be some risks in taking it, so the actual risks may far outweigh the actual benefits.

Let’s take a look. Continue reading “Chloroquine for coronavirus, I mean the Trumpvirus – evidence is weak”

Coronavirus vaccines – massive list of vaccine candidates for COVID-19

coronavirus vaccines

Because of the ongoing COVID-19 pandemic, the interest in coronavirus vaccines has been quite high (to say the least). I have been keeping an updated list of vaccine candidates in another article, but it was becoming so cumbersome to update, and I wanted to make information clearer to read, I decided to completely rewrite it.

This article about coronavirus vaccines will also be regularly updated, so stay tuned. Continue reading “Coronavirus vaccines – massive list of vaccine candidates for COVID-19”

Corvelva vaccine research – here we go again with pseudoscience

Corvelva vaccine research

And here we go with one more attempt by the vaccine deniers to prove their worthless claims – more Corvelva vaccine research that is pure, unfettered pseudoscience. And to make sure that they can claim their research is peer-reviewed, they take the well-worn science denier’s method of publishing their garbage wherever they can. 

Although Corvelva vaccine research consists of producing data that is laughably bad, I have to keep picking it apart, because we all know anti-vaxxers everywhere will use it as if it is worthy of a Nobel Prize. To be fair, it might be as valuable as a Nobel Prize, since the article can be used as toilet paper, and we know how important that is these days

So, time to take down more Corvelva vaccine research. And it’s as bad as it always is. Continue reading “Corvelva vaccine research – here we go again with pseudoscience”

Coronavirus vaccine testing – pro-vaxxers want to “take a risk” with testing

coronavirus vaccine testing

Time for something completely different – I keep reading statements by pro-vaccine people that they want to shorten coronavirus vaccine testing to get it out to the people faster. Let me slam on those brakes because nothing could be worse for public health than to engage in that type of thinking.

As I’ve written on a number of occasions, coronavirus vaccine testing is going to take a long time. Publicly, some “experts” are claiming that a vaccine might take 18 months, but that’s only if everything goes right. And since it always doesn’t go right, I would bet that it would take 4-5 years before we see a coronavirus vaccine.

Because of this pandemic has become very dangerous, and there are no “cures” right now (despite Donald Trump’s ignorance about chloroquine), the desire for a vaccine has become very loud and very annoying. 

But to speed up coronavirus vaccine testing is dangerous. And let me explain why. Continue reading “Coronavirus vaccine testing – pro-vaxxers want to “take a risk” with testing”

BCG vaccine for COVID-19 – is a 100-year-old vaccine beneficial?

lung cancer vaccine

Ignoring quackery and Trump’s ignorance about chloroquine, it seems like everyone is throwing stuff at the wall to see if it works. Recently, while researching an article on coronavirus vaccines, I noticed that some were pushing the BCG vaccine for COVID-19.

I wanted to see if there was any evidence supporting the BCG vaccine for COVID-19, so here’s what I found. Continue reading “BCG vaccine for COVID-19 – is a 100-year-old vaccine beneficial?”

COVID-19 vaccine research for coronavirus – updated 26 March 2020

COVID-19 vaccine

This article about COVID-19 vaccine research has been completely updated and can be found here. The comments section for this article has been closed.

Because the development of a potential COVID-19 vaccine is of massive interest currently, and because I have a passion for vaccine research and development, this article will a guide for vaccines involved with the coronavirus. It will be updated regularly, and I will post to social media when it is updated.

Right now, there are several COVID-19 vaccine candidates being developed by large and small pharmaceutical companies. Of course, social media will make it sound like they are all just around the corner, and they will all work.

It doesn’t work that way, so let me keep you updated with this guide to COVID-19 vaccine research and development. Continue reading “COVID-19 vaccine research for coronavirus – updated 26 March 2020”

Flu vaccine for COVID-19 – why you should be vaccinated soon

Flu vaccine for COVID-19

Yes, this article will discuss the flu vaccine for COVID-19 (the current coronavirus outbreak). But for those of you who don’t just read headlines, no, I am not suggesting that the flu vaccine will prevent a coronavirus infection.

As I wrote recently, a coronavirus vaccine is years away from reality. Any suggestion otherwise depends upon magical thinking and beliefs, not in evidence. But there are many things we can do that may prevent the most severe complications from the disease. Continue reading “Flu vaccine for COVID-19 – why you should be vaccinated soon”

Coronavirus vaccine development – Donald Trump gets it all wrong again

coronavirus vaccine

Donald Trump’s ignorant comments about how the COVID-19 pandemic would be over by April makes people believe there is a coronavirus vaccine just around the corner. There isn’t. 

Of course, Trump is ignorant about the vast swaths of science from climate change to vaccines, so if he says anything about science, it should be immediately ignored.

Even if he claimed that the blue sky was caused refraction of light, I’d immediately go outside, check the color of the sky, then pull out a physics textbook to confirm what he said. I’m that skeptical of anything that comes out of his ignorant, anti-science mouth.

His claim that the epidemic will be over by April is in direct opposition to real scientists and experts at the CDC, WHO, and elsewhere, all of whom are extremely concerned about a coronavirus pandemic.

His comments, and questions across the internet, seem to imply that a coronavirus vaccine is around the corner, and we shouldn’t worry. Nothing could be further from the truth.

Let’s take a look at vaccine development, and I am going to especially focus on some of the technical challenges for a coronavirus vaccine. Just because we need some fact-based evidence so that pro- and anti-vaccine people understand what’s going on.

I’m assuming that most anti-vaxxers will publicly or secretly get the coronavirus vaccine. Just a guess, but maybe they’ll get information here first.

Continue reading “Coronavirus vaccine development – Donald Trump gets it all wrong again”