Pertussis vaccine waning effectiveness – the facts

pertussis vaccine waning effectiveness

The issues with the pertussis vaccine waning effectiveness has been circulating for several years. There have been a number of well-designed studies that have provided evidence of the issues with the pertussis component of the DTaP or Tdap vaccine (which also provides immunization against tetanus and diphtheria, both dangerous diseases).

According to current research, individuals who have been vaccinated against whooping cough (Bordetella pertussis), with either the DTaP (version for usually for children) or Tdap vaccine, lose protection against whooping cough in some time period after being vaccinated.

A new article, published in Pediatrics, written by Nicola P Klein et al.,  examined children who received the Tdap vaccine in the Kaiser Permanente Northern California (KPNC) health care plan, a vertically integrated managed care system which closely tracks patients after vaccination. Their data provide important information about the strategies for the vaccine going forward.

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Why we vaccinate – pertussis and epilepsy are linked

There is really only one reason to vaccinate – protecting everyone, especially children, from dangerous vaccine preventable diseases. We have eliminated smallpox. We have almost eliminated polio.

And we had almost made measles extinct, until the myth that the MMR vaccine (to prevent mumps, measles and rubella) caused autism, started by one of sciences greatest fraudsters, the defrocked MrAndy Wakefield. It’s a myth that’s been thoroughly and definitively debunked.

One vaccine preventable infectious disease that we’ve been unable to conquer is  whooping cough (caused by the bacteria, Bordetella pertussis), also known as pertussis. Pertussis is a relatively dangerous infection, the disease itself has serious consequences for children and adults:

  • 1 in 4 (23%) get pneumonia (lung infection)
  • 1 or 2 in 100 (1.6%) will have convulsions (violent, uncontrolled shaking)
  • Two thirds (67%) will have apnea (slowed or stopped breathing)
  • 1 in 300 (0.4%) will have encephalopathy (disease of the brain)
  • 1 or 2 in 100 (1.6%) will die

Whooping cough can be easily prevented by the DTaP or Tdap vaccines (which also protect against tetanus and diphtheria). The vaccines can be given to infants as early as 6 weeks to 2 months old.

As with all medical procedures, there are some adverse effects with the pertussis vaccines. Moderate adverse effects from the vaccine occur in about 1 in 10,000 (or even fewer) injections. The most severe effects, which may or may not be causally related to the vaccine since the rate is  so low, are in the range of 1 out of a million doses.

One out of one million doses of the vaccine cause a serious adverse event (maybe). Compare that to the 1-2 out of 100 will die of the disease. Unless you flunk math, there is no rational reason to avoid the vaccine. Continue reading “Why we vaccinate – pertussis and epilepsy are linked”

Homeopathy, Honesty, and Consumer Protection

Editor’s note: This article was originally published in January 2015. It has been revised to include information from a recent Australian Federal Court ruling that imposed fines upon the homeopaths.

On December 22, 2014 an Australian Federal Court ruled that Homeopathy Plus! Pty Ltd, LTD, and its creator and director, Ms. Frances Sheffield, engaged in misleading conduct in trade or commerce in making claims against the whooping cough vaccine and in support of homeopathic remedies as an alternative – or a second line of defense – for preventing whooping cough.

This was done after the Australian Competition and Consumer Commission (ACCC) asked the court to declare that it’s misleading and impose other penalties (detailed description of the court proceedings, and more information). In other words, they were asked to look into homeopathy honesty.

This article has two objectives:

  1. Provide a brief overview and summary of the decision.
  2. Determine whether similar action can be taken against those making similar claims in the United States.

Continue reading “Homeopathy, Honesty, and Consumer Protection”

Vaccines saved lives – scientific evidence

There are many canards propagated by the vaccine deniers to support their personal beliefs (really, denialism) about the safety and effectiveness of vaccines. One of their more popular beliefs is that vaccines didn’t end many of the deadly diseases, but improved sanitation, healthcare, nutrition or magical fairies (also known as homeopathy) ended these diseases.

There is even a subgroup of these believers who think that the CDC, historians, and everyone else is lying about the epidemics that existed prior to vaccinations–let’s call this group history deniers. They reject the scientific and historical evidence that vaccines saved lives – amazing.

So, is there scientific evidence that vaccines actually ended these epidemics? Yes there is, and it’s unequivocal. Unless you want to embrace historical revisionism, and somehow all of the health care records and epidemiological information was faked, vaccines saved lives – lots of lives. Continue reading “Vaccines saved lives – scientific evidence”

Vaccine preventable diseases – much scarier than vaccines

Debunking anti-vaccine myths are one of the goals of this blog, which has evolved from my original intent of mocking anti-evolution lies. Mostly, the tactics of both science deniers are the same, so most of what I write is interchangeable–it was a natural evolution to vaccines.

Yes, I went there.

There are several tactics to criticizing the anti vaccination cult. For me, it’s being pejorative (hey, I call them a cult), being rude, and mocking them with all the fervor I can find in my brain. Since ALL of the evidence supports the fact that vaccines are relatively safe and very effective, short of someone actually bring the same volume of science that disputes that fact, making fun of the cult is my reason to exist.

I know my tactics aren’t very popular in the pro-vaccine world–I really have fun doing it.

Just so all of you understand this clearly, I do not discriminate in my mockery of pseudoscience. I’ve done much worse to the anti-evolution gang. And don’t get me started on the purveyors of junk medicine, like chiropractic, acupuncture and homeopathy–I seriously enjoy making fun of them all.

However, most pro vaccine writers are much more civil. Dorit Rubinstein Reiss, who writes here frequently, is quite courteous towards the anti-vaccination movement, despite the bigoted hatred that they send her way. Some of us think that she’s treated so badly probably because she’s so polite and civil.

To be fair, most pro-vaccine writers range from snarky and pointed to civil and supportive. Some writers try to hit a balance between the two extremes by being both tough and supportive (especially to that group that we all call “fence-sitters” who are the parents who aren’t sure about vaccines).

Dan Kahan, a Yale University law professor, has authored research that delves into cultural cognition which is the study of how individuals form beliefs about the amount of risk in certain situations based on their preconceived cultural notions of good behavior. He has called me out personally for using the “anti-science” trope with respect to evolution, climate change and vaccines.

Kahan presents some very convincing evidence that more civil discussions with vaccine deniers can be more helpful–obviously, I disagree, but Professor Kahan makes extremely valid points. I’m glad that there are dozens of other pro-vaccine websites who meet or exceed his recommendations on civility. I’m too exhausted from decades of fighting against pseudoscience and straight out science denialism to change my methods now. Like I said, I’m having too much fun doing it my way.

However, there seems to be a third way to deal with the anti-vaccination crowd. It probably will not convince the true believers who think that evidence is only what supports their point of view, like the crackpots at Age of Lying about Autism who still think that MrAndy Wakefield is some sort of hero.

No, it’s the fence sitters who should know the facts about vaccine preventable diseases – it should scare the crap out of them. Continue reading “Vaccine preventable diseases – much scarier than vaccines”

Whooping cough outbreak – science and simple math

I have written extensively about several whooping cough (Bordetella pertussis) outbreaks which had reached epidemic levels in areas like the Washington state, which had been considered one of the worst outbreaks in the USA during the past several decades. The outbreak has lead to several deaths here in the USA and in other countries such as the UK.

Of course, these outbreaks and epidemics have lead to the “blame game” from the antivaccination cult, because they have claimed that since A) most kids are vaccinated, and B) we’re having this outbreak, then C) either the vaccines are useless or are actually the cause of the outbreak. Seriously. They blame the vaccines.

There have been numerous reports about a whooping cough outbreak in the Reno County, KS area, with about 70 cases of the disease being reported. The report indicates that most of the kids who have the disease were vaccinated. It is unclear who said this, and what are the actual statistics. But for now, we’ll take this at face value.

Since this outbreak will undoubtedly lead to the typical antivaccine rhetoric about the whooping cough vaccines, DTaP or Tdap (which also protect against tetanus and diphtheria), I decided to search the internet to find the most popular vaccine denialist arguments regarding pertussis vaccinations–then debunk them. Hopefully, this will be useful for those who are observing what’s going on in Reno.

Continue reading “Whooping cough outbreak – science and simple math”

Anti vaccine cult uses Hitler’s Big Lie – laughable strategy

 

OK I apologize. I went full-Godwin with the title. In case you don’t know, I’m referring to Godwin’s Law, named after Mike Godwin, who asserted that “as an online discussion grows longer, the probability of a comparison involving Nazis or Hitler approaches 1.” In other words, in an online argument, it’s almost a guarantee that someone will invoke a reference to Hitler or Nazis as the discussion gets more and more heated.

Because I am all about efficiency, I decided to invoke Hitler right in the title. Actually, given some of the antisemitism and hate speech of the antivaccine fanatics, it’s probably not too far off.

Be that as it may, the anti vaccine cult loves the propaganda technique known as the Big Lie, which is a method of stating and repeating a falsehood, then treating it as if it is self-evidently true with the goal of swaying the course of an argument. Eventually, it is hoped by the proponents of the Big Lie, that it will be taken for granted, and not really critically questioned. Hitler, and his Nazi propaganda machine, used the Big Lie to blame all of Germany’s problems, prior to World War II, on Jews, which may have contributed to the German people’s support, either actively or passively, of the Holocaust.

It’s ironic that some of the basic antivaccination ad hominem hate speech tends to be extremely antisemitic, especially towards the publicly Jewish members of the pro-vaccine/pro-science side. It’s doubly ironic that the anti vaccine cult utilizes Nazi propaganda strategies, while claiming that vaccination, especially mandatory vaccination, is somehow a modern day holocaust. Truthfully, there’s really not any mandatory (and certainly not forced) vaccination of anyone in the developed world. There are so many loopholes for those who refuse vaccines through various exemptions, that mandatory is truly not that mandatory.

Of course, comparing vaccinations to the Holocaust is a form of Holocaust denial, just as dangerous as climate change denial, evolution denial, or all other forms of denialism. In this case, comparing vaccination, which saves lives, to the Holocaust (in this definition, the murder of European Jews), which end the lives 6 million innocent human beings, either betrays their lack of knowledge of vaccines and the Holocaust, or worse, that they think the sharp temporary pain of an immunization is somewhat equivalent to the murder of 6 million Jews.

The fact that there is little evidence that anyone has ever died of a vaccination (stay tuned, an article is coming from here, once all the research is done) compared to mountains of evidence that the Holocaust actually happened makes such comparisons ignorant and hateful. Period. Continue reading “Anti vaccine cult uses Hitler’s Big Lie – laughable strategy”

California’s vaccine exemption laws – clustering effects

All 50 US states (along with several territories and DC) require mandatory vaccination for children entering public (and frequently, private) schools. This system has essentially ended most vaccine preventable diseases in the USA, including measles, polio, chickenpox, and many others.

Broad vaccination is considered one of the 10 greatest achievements in public health. Vaccines should probably be number 1 on the list. Overall, the immunization mandate has established a strong herd effect, which has generally ended transmission of these diseases.

Even though vaccinating children before they enter school is mandatory, there are ways around it, if you choose. Every state allows medical exemptions, which is based on a proven risk for a child to not be vaccinated with one or more vaccines. For example, some vaccines are produced in chicken eggs, and a tiny percentage of children are allergic. Medical exemptions are absolutely critical to the well being of the child, and no pro-science (pro-vaccine) writer or researcher would be opposed to those types of exemptions.

Furthermore, most states have vaccine exemption laws which allows personal belief exemptions (PBE). These PBEs fall into one of two groups–religious exemptions, that is, the parent “claims” that their religion is opposed to vaccines; or personal exemptions, which are simply based on the fact that the parents are opposed to vaccination for whatever reason that hits their brain after 20 minutes of Googling “facts.”

Most states allow both types of exemptions, some only allow religious exemptions, and one state, Mississippi, allows only medical exemptions. As a progressive, there is little positive I can say about Mississippi, but this is a major positive. So congrats Mississippi for caring about children, at least in this one important way. Continue reading “California’s vaccine exemption laws – clustering effects”

Why we vaccinate–to protect our children from pertussis

 

tdap-mother-pertussis

During this past week, a 25 day old baby in Santa Barbara, CA died from pertussis, commonly known as whooping cough (caused by the Bordetella pertussis bacteria). The disease can be easily prevented by the DTaP or Tdap vaccines (also protect against tetanus and diphtheria), which can be given to infants as early as 6 weeks to 2 months old.

According to the California Department of Public Health, infants who are too young to be fully immunized or those who are not vaccinated are most vulnerable to severe and fatal cases of pertussis. In 2014, 66 of the pertussis hospitalizations cases were children four months of age or younger. Two infants have died of pertussis in California during 2014. Continue reading “Why we vaccinate–to protect our children from pertussis”

2013-14 vaccine uptake in the USA is still high

voices-for-vaccinesDespite the continued social network misinformation about vaccine safety and/or effectiveness, the United States Centers for Disease Control and Prevention (CDC) has reported that the median vaccination coverage, amongst children between the age of 19-35 months was 94.7% for 2 doses of measles, mumps, and rubella (MMR) vaccine; 95.0% for varying local requirements for diphtheria, tetanus toxoid, and acellular pertussis (DTaP) vaccine; and 93.3% for 2 doses of varicella vaccine among those states with a 2-dose requirement.

The median total exemption rate was 1.8%, a difficult number to truly analyze. The CDC reported many issues like some parents get an exemption even after their children are fully or partially vaccinated, some exemptions are used as a matter of convenience because the parents forgot to vaccinated, and some states don’t report exemptions. Moreover, the CDC data indicates up to 15% of exemptions are “medical,” meaning that a child cannot receive a vaccine as a result of an establish medical contraindication.

Although these numbers fall near the 95% vaccination rate goal establish by the CDC’s Health People 2020there is still a concern that clusters of unvaccinated or under-vaccinated children exist in many states and areas. Those locations become susceptible to outbreaks of vaccine-preventable diseases. Moreover, 26 states and DC failed to meet the 95% goal, so the disparity between vaccinated and unvaccinated groups remain large.

The research also shows that there have been no statistically significant changes in either vaccination or exemption rate from 2012-13. This is more statistical support that the antivaccination agenda is not gaining much traction across most of the USA.

Continue reading “2013-14 vaccine uptake in the USA is still high”