Why we vaccinate-flu vaccine reduces cardiovascular risks

senior-flu-vaccineIn addition to preventing the infection, the flu vaccination may have a more important benefit for those who get the shot. A new systematic review, published this week in the Journal of the American Medical Association (JAMA), found that individuals vaccinated against the flu had a significantly lower risk of a major cardiovascular events, such as a heart attack or stroke, compared with those who received no flu vaccine.

In the meta-review, researchers from the University of Toronto analyzed five published studies and one unpublished study. They then rolled-up the data to investigate the connection between those who were vaccinated against the flu and various cardiovascular events. Altogether, the studies included approximately 6000 patients. Moreover, the patients had an average age of 67, while about one-third had a medical history of heart disease.

The results were dramatic–individuals who were vaccinated against the flu had a 2.9% risk of having a major cardiovascular even with the next eight months. The risk for those who were not vaccinated (or received a placebo) increased by 150% to 4.7%, a statistically significant difference.

Just to be clear, the study did not show that getting the flu virus caused the development of cardiovascular disease. However, patients with diagnosed cardiovascular disease (or who have had cardiovascular events, such as myocardial infarction) are at a significantly greater risk of another one if they catch the flu. As the authors state, “the greatest treatment effect was seen among the highest-risk patients with more active coronary disease.”

According to the study, less than 50% of people under the age of 65 with high-risk conditions (such as cardiovascular disease) receive the flu vaccine, which puts them at risk of complications like heart attack and stroke. Older individuals, who often have existing health problems, appear to be more likely to be vaccinated, although up to one third still skip their annual flu shot.

One last point–getting the vaccine, whether the patient has underlying cardiovascular disease or not, does not increase the risk of any cardiovascular effects.

We’ve all heard the excuses and myths about the flu vaccines. They just aren’t trueNo, they really really really aren’t true. By the way, Mark Crislip, MD, thinks those of you who make up whiny excuses for not getting the flu vaccine are dumbasses. His words, but quite apropos.

So, if you have had cardiovascular disease, or are at risk from it (like those who have type 1 or 2 diabetes), then get a flu vaccination no matter what your age is. If you have any other risk factors, like being under the age of 5, pregnant, or other important chronic conditions, get a flu immunization. If you’re a healthy adult, and you’re going to visit your parents or grandparents who could catch the flu from you, get vaccinated, even if they’ve been vaccinated (because there is some small chance that the vaccine didn’t give them full immunity). Just get vaccinated for the flu.

The clinical value of preventing the flu is huge. The mythical risks of getting the vaccine are invisible.

If you need to search for accurate information and evidence about vaccines try the Science-based Vaccine Search Engine.

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Stem cell treatments for heart attacks

Acute myocardial infarctions (AMI), commonly known as heart attacks, are responsible for about 12.6% of deaths worldwide, according to The World Health Report 2004 – Changing History.  In the United States, about 16.6% of those who have heart attacks die within 30 days of the attack.  Outside of AIDS and a few infectious diseases, AMI is the biggest killer of adults.

An AMI is essentially caused by a blockage of the coronary arteries which leads to cellular damage of some of the heart muscle (myocardium).  This prognosis can be minor to deadly, depending on a lot of issues such as other cardiovascular risk profile (diabetes, peripheral vascular disease, smoking and others), quality of treatment, and severity of the tissue damage.  Over the past few years, treatments have improved the outlook for AMI sufferers, but the risk of a subsequent heart attacks and mortality rates are still high. Continue reading “Stem cell treatments for heart attacks”