Celiac disease (also known as coeliac disease in British English speaking countries) is an autoimmune disorder that afflicts the small intestine of certain individuals who are genetically predisposed to it. The disease afflicts between 1 in 1,750 and 1 in 105 people in the United States (or about 200,000 to 3,000,000 people) and usually, but not always, results in chronic diarrhea, low pediatric weight gain, and fatigue. This disease is caused by a reaction to a gluten protein found in wheat, and similar proteins found common grains such as barley and rye.
Upon exposure to gluten, the immune system causes an inflammatory reaction of the lining the small intestine. This interferes with the absorption of nutrients. The only known effective treatment is a lifelong gluten-free diet. This disease should not be confused with wheat allergy, which is also caused by a reaction to wheat proteins. Continue reading “Vaccine to block gluten sensitivity in celiac disease”